Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745024 | 0.94 | TSHR (0.39) | POLBPKML3MBTL1KDM4ETSHR | |
| SCHEMBL4814034 | 0.77 | DHFR (0.38) | L3MBTL1KDM4ETSHRGAANISCH | |
| SCHEMBL9517850 | 0.71 | PPARG (0.45) | POLBPKML3MBTL1KDM4ETSHR | |
| SCHEMBL4070724 | 0.68 | NISCH (0.51) | POLBL3MBTL1TSHRGAANISCH | |
| SCHEMBL9520667 | 0.68 | SMN1; SMN2 (0.49) | POLBPKML3MBTL1KDM4ETSHR | |
| Bromide SCHEMBL4909528 | 0.67 | NISCH (0.50) | POLBL3MBTL1TSHRGAANISCH | |
| Formic Acid SCHEMBL4911933 | 0.64 | L3MBTL1 (0.53) | POLBL3MBTL1TSHRGAAPTPRC | |
| Formic Acid SCHEMBL4823088 | 0.63 | NISCH (0.67) | TSHRGAANISCHALDH1A1HPGD | |
| SCHEMBL4825348 | 0.62 | NISCH (0.52) | TSHRGAANISCH | |
| Formic Acid SCHEMBL4911292 | 0.62 | SMN1; SMN2 (0.36) | POLBTSHRGAANISCHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375125-B2 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |