Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.86 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TUBB | P07437 | 1/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fleroxacin SCHEMBL29377022 | 0.92 | KDM4E (1.00) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| Fleroxacin SCHEMBL48145 | 0.92 | KDM4E (1.00) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| Fleroxacin SCHEMBL9745354 | 0.91 | KDM4E (0.98) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL21783262 | 0.91 | KDM4E (0.86) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| Fleroxacin SCHEMBL11193870 | 0.91 | KDM4E (0.98) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| Fleroxacin SCHEMBL9745337 | 0.91 | KDM4E (0.98) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL9636841 | 0.91 | KDM4E (0.71) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| Fleroxacin SCHEMBL29114441 | 0.90 | KDM4E (0.96) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL312380 | 0.90 | KDM4E (0.84) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11187784 | 0.89 | KDM4E (0.68) | KDM4EADRA2BMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093381-B2 | Method of synthesis of fluoroquinolones | BIOCODEX (FR) | 2012-01-10 | — | — | US | disclosed |
| US-20090054643-A1 | NOVEL METHOD OF SYNTHESIS OF FLUOROQUINOLONES | BIOCODEX (FR) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054643-A1 | NOVEL METHOD OF SYNTHESIS OF FLUOROQUINOLONES | NQO2, Q6ZSR9, QARS1 | KDM4E 2435/4885ADRA2B 1209/4885MAPK1 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.