Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.86 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | HPGD | P15428 | 7/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TUBB | P07437 | 1/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fleroxacin SCHEMBL29377022 | 0.92 | KDM4E (1.00) | KDM4EDRD3ADRA2BMAPK1ALDH1A1 | |
| Fleroxacin SCHEMBL48145 | 0.92 | KDM4E (1.00) | KDM4EDRD3ADRA2BMAPK1ALDH1A1 | |
| SCHEMBL312380 | 0.92 | KDM4E (0.84) | KDM4EDRD3ADRA2BMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10766749 | 0.92 | KDM4E (0.72) | KDM4EDRD3ADRA2BMAPK1ALDH1A1 | |
| Fleroxacin SCHEMBL11193870 | 0.91 | KDM4E (0.98) | KDM4EDRD3ADRA2BMAPK1ALDH1A1 | |
| SCHEMBL312186 | 0.91 | KDM4E (0.86) | KDM4EDRD3ADRA2BMAPK1ALDH1A1 | |
| Fleroxacin SCHEMBL9745354 | 0.91 | KDM4E (0.98) | KDM4EDRD3ADRA2BMAPK1ALDH1A1 | |
| Fleroxacin SCHEMBL9745337 | 0.91 | KDM4E (0.98) | KDM4EDRD3ADRA2BMAPK1ALDH1A1 | |
| Fleroxacin SCHEMBL29114441 | 0.90 | KDM4E (0.96) | KDM4EDRD3ADRA2BMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11187466 | 0.89 | KDM4E (0.68) | KDM4EDRD3ADRA2BMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020014269-A9 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC, LLC. (US) | 2020-03-05 | — | — | WO | disclosed |