SCHEMBL4814940

SCHEMBL4814940

CCC=CCC=CCC=CCC=CCC=CCC=CCCC(=O)Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.67
CYP19A1 P11511 4/20 0.67
MAPT P10636 4/20 0.67
PPARG P37231 3/20 0.67
OXER1 Q8TDS5 3/20 0.67
RXRA P19793 2/20 0.67
FFAR1 O14842 2/20 0.67
F7 P08709 3/20 0.57
F3 P13726 3/20 0.57
PPARA Q07869 3/20 0.57
PTGS1 P23219 3/20 0.57
KMT2A Q03164 2/20 0.57
PPARD Q03181 2/20 0.57
ADORA3 P0DMS8 2/20 0.57
NR1I2 O75469 2/20 0.53
PTGS2 P35354 2/20 0.53
CYP3A4 P08684 2/20 0.53
ALOX15 P16050 2/20 0.53
HSD17B10 Q99714 2/20 0.53
TDP1 Q9NUW8 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5296481 1.00 ALDH1A1 (0.67) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL4814932 1.00 ALDH1A1 (0.67) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL9797172 1.00 ALDH1A1 (0.67) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL13749756 0.93
SCHEMBL38661876 0.88 ALDH1A1 (0.69) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL9463025 0.88 ALDH1A1 (0.69) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL18555769 0.88 ALDH1A1 (0.69) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL4804537 0.88 ALDH1A1 (0.69) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL9463022 0.88 ALDH1A1 (0.69) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL4804548 0.88 ALDH1A1 (0.69) ALDH1A1CYP19A1MAPTPPARGOXER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE40546-E1 1,3-Propane diol esters and ethers and methods for their use in drug delivery SCARISTA, LTD. (GB) 2008-10-21 US disclosed
US-RE40480-E1 1,3-Propane diol esters and ethers and methods for their use in drug delivery SCARISTA LIMITED (GB) 2008-09-02 US disclosed
WO-2007006543-A1 CAMPTOTHECIN ANALOGUES, PROCESS FOR THEIR PREPARATION, USE AND FORMULATIONS CONTAINING THEM INDENA S.P.A. (IT) 2007-01-18 WO disclosed
EP-0614896-B1 Esculetin derivatives and pharmaceutical composition KUREHA CHEMICAL IND CO LTD (JP) 1998-12-30 EP disclosed
WO-1998040059-A1 UNSATURATED FATTY ACID ANHYDRIDES FOR USE IN THERAPY SCOTIA HOLDINGS PLC (GB) 1998-09-17 WO disclosed
EP-0823889-A1 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS SCOTIA HOLDINGS PLC (GB) 1998-02-18 EP disclosed
WO-1996034846-A1 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS SCOTIA HOLDINGS PLC (GB) 1996-11-07 WO disclosed
US-5455268-A Treating arthropathy KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-10-03 US disclosed
EP-0614896-A1 Esculetin derivatives and pharmaceutical composition KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1994-09-14 EP disclosed
EP-0409939-A1 USE OF POLYUNSATURATED FATTY ACID DERIVATIVES IN THE PREPARATION OF MEDICAMENTS WITH TYROSINE KINASE INHIBITING ACTIVITY BIOSIGNAL Kutato Fejleszto Kft. (HU) 1991-01-30 EP disclosed
WO-1990008130-A1 POLYUNSATURATED FATTY ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, METHOD FOR THE PREPARATION THEREOF, AND THEIR USE AS MEDICAMENT FOLLIGEN BUDAPEST LTD. (HU) 1990-07-26 WO disclosed