SCHEMBL4814932

SCHEMBL4814932

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.67
CYP19A1 P11511 4/20 0.67
MAPT P10636 4/20 0.67
PPARG P37231 3/20 0.67
OXER1 Q8TDS5 3/20 0.67
RXRA P19793 2/20 0.67
FFAR1 O14842 2/20 0.67
F7 P08709 3/20 0.57
F3 P13726 3/20 0.57
PPARA Q07869 3/20 0.57
PTGS1 P23219 3/20 0.57
KMT2A Q03164 2/20 0.57
PPARD Q03181 2/20 0.57
ADORA3 P0DMS8 2/20 0.57
NR1I2 O75469 2/20 0.53
PTGS2 P35354 2/20 0.53
CYP3A4 P08684 2/20 0.53
ALOX15 P16050 2/20 0.53
HSD17B10 Q99714 2/20 0.53
TDP1 Q9NUW8 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4814940 1.00 ALDH1A1 (0.67) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL5296481 1.00 ALDH1A1 (0.67) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL9797172 1.00 ALDH1A1 (0.67) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL13749756 0.93
SCHEMBL38661876 0.88 ALDH1A1 (0.69) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL9463025 0.88 ALDH1A1 (0.69) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL18555769 0.88 ALDH1A1 (0.69) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL4804537 0.88 ALDH1A1 (0.69) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL9463022 0.88 ALDH1A1 (0.69) ALDH1A1CYP19A1MAPTPPARGOXER1
SCHEMBL4804548 0.88 ALDH1A1 (0.69) ALDH1A1CYP19A1MAPTPPARGOXER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4569012-A1 EFFICIENT SYNTHESIS OF VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS University of Utah Research Foundation (US) 2025-06-18 EP disclosed
WO-2024035945-A1 EFFICIENT SYNTHESIS OF VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2024-02-15 WO disclosed
WO-2024035945-A1 EFFICIENT SYNTHESIS OF VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2024-02-15 WO disclosed
US-9956302-B2 Compounds and compositions for the treatment of ocular disorders Graybug Vision, Inc. (US) 2018-05-01 US disclosed
US-9956302-B2 Compounds and compositions for the treatment of ocular disorders Graybug Vision, Inc. (US) 2018-05-01 US disclosed
US-20180110864-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS Graybug Vision, Inc. (US) 2018-04-26 US disclosed
US-20180110864-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS Graybug Vision, Inc. (US) 2018-04-26 US disclosed
US-20180104350-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS Graybug Vision, Inc. (US) 2018-04-19 US disclosed
US-20180104350-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS Graybug Vision, Inc. (US) 2018-04-19 US disclosed
US-20180064823-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS Graybug Vision, Inc. (US) 2018-03-08 US disclosed
US-RE43632-E1 1,3-propane diol esters and ethers and methods for their use in drug delivery SCARISTA, LTD. (GB) 2012-09-04 US disclosed
US-20120035250-A1 PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING PHENOMENOME DISCOVERIES INC. (CA) 2012-02-09 US disclosed
US-20120035250-A1 PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING PHENOMENOME DISCOVERIES INC. (CA) 2012-02-09 US disclosed
WO-2010071988-A1 PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING PHENOMENOME DISCOVERIES INC. (CA) 2010-07-01 WO disclosed
US-RE40546-E1 1,3-Propane diol esters and ethers and methods for their use in drug delivery SCARISTA, LTD. (GB) 2008-10-21 US disclosed
US-RE40480-E1 1,3-Propane diol esters and ethers and methods for their use in drug delivery SCARISTA LIMITED (GB) 2008-09-02 US disclosed
US-6555700-B1 Bioactives (drugs, nutrients) in a form in which they are lipophilic so that they can pass lipid barriers (membranes, skin etc.) in the body readily; glycerides of esterified, aminated or etherified bioactives; side effect reduction SCOTIA HOLDINGS PLC (GB) 2003-04-29 US disclosed
WO-1998040059-A1 UNSATURATED FATTY ACID ANHYDRIDES FOR USE IN THERAPY SCOTIA HOLDINGS PLC (GB) 1998-09-17 WO disclosed
EP-0823889-A1 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS SCOTIA HOLDINGS PLC (GB) 1998-02-18 EP disclosed
WO-1996034846-A1 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS SCOTIA HOLDINGS PLC (GB) 1996-11-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035250-A1 PLASMALOGEN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR TREATING DISEASES OF THE AGING PHOSPHO1, SGMS2, MBOAT1 ALDH1A1 1960/4885CYP19A1 399/4885MAPT 158/4885
US-20180064823-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS PTGIR, PTGIS, CA2 ALDH1A1 1010/4885CYP19A1 1273/4885MAPT 2665/4885
US-20180110864-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS PTGIR, PTGIS, CA2 ALDH1A1 1010/4885CYP19A1 1273/4885MAPT 2665/4885
US-20180104350-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS PTGIR, PTGIS, CA2 ALDH1A1 1010/4885CYP19A1 1273/4885MAPT 2665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.