Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.64 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 5/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4808013 | 0.98 | DHODH (0.62) | DHODHCDK1CDK2AURKASRC | |
| SCHEMBL9820151 | 0.81 | MEN1 (0.65) | DHODHCDK2AURKASRCGSK3B | |
| SCHEMBL10294586 | 0.81 | AURKA (0.46) | DHODHAURKASRCGSK3BAURKB | |
| SCHEMBL9820128 | 0.79 | DHODH (0.60) | DHODHAURKAGSK3BAURKBMEN1 | |
| SCHEMBL11917491 | 0.79 | ULK1 (0.50) | DHODHAURKASRCGSK3BAURKB | |
| SCHEMBL14293657 | 0.78 | DHODH (0.59) | DHODHCDK2AURKASRCGSK3B | |
| SCHEMBL21247715 | 0.77 | CDK2 (0.76) | CDK1CDK2ALDH1A1GAAMAPT | |
| SCHEMBL12430732 | 0.77 | AURKA (0.84) | AURKASRCGSK3BAURKBPLK4 | |
| SCHEMBL4808746 | 0.76 | PIK3C3 (0.65) | DHODHCDK2AURKAGSK3BEGFR | |
| SCHEMBL13663574 | 0.74 | DHODH (0.55) | DHODHAURKASRCGSK3BAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329288-B2 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof | L'OREAL S.A. (FR) | 2008-02-12 | — | — | US | claimed |
| US-20060005323-A1 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | claimed |
| EP-1568694-A1 | N-heteroaryl-para-phenylene diamines for colouring hair | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| US-7329288-B2 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof | L'OREAL S.A. (FR) | 2008-02-12 | — | — | US | disclosed |
| US-7329288-B2 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof | L'OREAL S.A. (FR) | 2008-02-12 | — | — | US | disclosed |
| EP-1568694-A1 | N-heteroaryl-para-phenylene diamines for colouring hair | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |