Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | DHODH | Q02127 | 1/20 | 0.63 |
| ▸ | AURKA | O14965 | 10/20 | 0.62 |
| ▸ | GSK3B | P49841 | 6/20 | 0.62 |
| ▸ | SRC | P12931 | 4/20 | 0.62 |
| ▸ | IGF1R | P08069 | 2/20 | 0.59 |
| ▸ | PAK4 | O96013 | 2/20 | 0.58 |
| ▸ | PLK4 | O00444 | 1/20 | 0.58 |
| ▸ | ITK | Q08881 | 1/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13663476 | 0.87 | IGF1R (0.56) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL12430951 | 0.82 | AURKA (0.63) | MAPTAURKAGSK3BSRCIGF1R | |
| SCHEMBL4815907 | 0.81 | DHODH (0.64) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL10122920 | 0.81 | AURKA (0.65) | MEN1MAPTKMT2AALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL4808013 | 0.80 | DHODH (0.62) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL12430947 | 0.80 | AURKA (0.71) | AURKAGSK3BSRCIGF1RPAK4 | |
| SCHEMBL9820128 | 0.79 | DHODH (0.60) | MEN1MAPTKMT2AALDH1A1GAA | |
| SCHEMBL12430654 | 0.79 | AURKA (1.00) | AURKAGSK3BSRCIGF1RPAK4 | |
| SCHEMBL12430924 | 0.79 | AURKA (0.59) | MAPTTP53AURKAGSK3BSRC | |
| SCHEMBL30713745 | 0.78 | ALDH1A1 (1.00) | MEN1MAPTKMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248523-A1 | Pyrazoles | FISONS plc (GB) | 1987-12-09 | — | — | EP | claimed |
| EP-3091983-A1 | PRODUCTS AND PHARMACEUTICAL COMPOSITIONS | Intra-Cellular Therapies, Inc. (US) | 2016-11-16 | — | — | EP | disclosed |
| WO-2015106032-A1 | PRODUCTS AND PHARMACEUTICAL COMPOSITIONS | INTRA-CELLULAR THERAPIES, INC. (US) | 2015-07-16 | — | — | WO | disclosed |
| CN-101248050-A | Organic compounds | INTRA CELLULAR THERAPIES INC (US) | 2008-08-20 | — | — | CN | disclosed |
| EP-0248523-B1 | PYRAZOLES | FISONS plc (GB) | 1991-10-16 | — | — | EP | disclosed |
| US-4803216-A | Pyrazole-3-amines as anti-inflammatory agents | FISONS PLC (GB) | 1989-02-07 | — | — | US | disclosed |
| EP-0248523-A1 | Pyrazoles | FISONS plc (GB) | 1987-12-09 | — | — | EP | disclosed |