SCHEMBL481632

SCHEMBL481632

O=C(O)c1cccc(N2C(=O)c3c(Cl)c(Cl)c(Cl)c(Cl)c3C2=O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.67
CA12 O43570 1/20 0.67
CA9 Q16790 1/20 0.67
TYMS P04818 1/20 0.62
DPP8 Q6V1X1 1/20 0.58
KMT2A Q03164 7/20 0.58
MEN1 O00255 5/20 0.58
KDM4E B2RXH2 1/20 0.58
ALDH1A1 P00352 1/20 0.58
HPGD P15428 1/20 0.57
CA2 P00918 1/20 0.56
CA7 P43166 1/20 0.56
NR1H3 Q13133 4/20 0.55
POLB P06746 3/20 0.54
MAPK1 P28482 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.53
NR1H2 P55055 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.51
RXFP1 Q9HBX9 1/20 0.51
APEX1 P27695 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11648165 0.85 KMT2A (0.62) TYMSKMT2AMEN1KDM4EALDH1A1
SCHEMBL513175 0.81 CA12 (0.69) CA1CA12CA9TYMSKMT2A
SCHEMBL20511484 0.80 CA9 (1.00) CA1CA12CA9KDM4EHPGD
SCHEMBL29549557 0.79 TYMS (0.71) CA1CA12CA9TYMSKMT2A
SCHEMBL7825377 0.79 TYMS (0.71) CA1CA12CA9TYMSKMT2A
SCHEMBL14172750 0.78 KMT2A (0.72) CA12CA9TYMSKMT2AMEN1
SCHEMBL3680527 0.77 DPP8 (0.65) CA1CA12CA9DPP8CA2
SCHEMBL4230581 0.76 S100B (0.74) CA1CA9TYMSKMT2AMEN1
SCHEMBL8108270 0.75 CA1 (0.52) CA1CA12CA9DPP8ALDH1A1
SCHEMBL9871954 0.75 TYMS (0.58) TYMSKMT2AMEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US claimed
EP-1465935-B1 PIGMENT COMPOSITIONS WITH MODIFIED ATRP COPOLYMER DISPERSANTS BASF SE (DE) 2016-09-07 EP disclosed
EP-1465935-B1 PIGMENT COMPOSITIONS WITH MODIFIED ATRP COPOLYMER DISPERSANTS BASF SE (DE) 2016-09-07 EP disclosed
EP-2411437-B9 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK CHEMIE GMBH (DE) 2013-07-31 EP disclosed
EP-2411437-B1 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK CHEMIE GMBH (DE) 2013-05-08 EP disclosed
EP-1611197-B1 LIGHT STABILISING POLYMER DISPERSANTS IN PIGMENT DISPERSIONS BASF SE (DE) 2012-03-21 EP disclosed
US-20120029104-A1 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK-CHEMIE GMBH (DE) 2012-02-02 US disclosed
EP-2411437-A2 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK-Chemie GmbH (DE) 2012-02-01 EP disclosed
WO-2010108672-A2 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK-CHEMIE GMBH (DE) 2010-09-30 WO disclosed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-20060229407-A1 Light stabilising polymer dispersants in pigment dispersions CIBA SPECIALTY CHEMICALS CORP. 2006-10-12 US disclosed
US-20060160940-A1 Process for intercalating natural or szynthetic clays with block or comb copolymers CIBA SPECIALTY CHEMICALS CORP. 2006-07-20 US disclosed
US-6849679-B2 Pigment compositions with modified block copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-02-01 US disclosed