SCHEMBL513175

SCHEMBL513175

O=C(O)c1cccc(N2C(=O)c3cc(Cl)c(Cl)cc3C2=O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.69
CA1 P00915 1/20 0.69
CA9 Q16790 1/20 0.69
KMT2A Q03164 8/20 0.69
MEN1 O00255 6/20 0.69
ALDH1A1 P00352 2/20 0.69
KDM4E B2RXH2 1/20 0.69
POLB P06746 3/20 0.64
MAPK1 P28482 1/20 0.64
TYMS P04818 1/20 0.62
RXFP1 Q9HBX9 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.60
S100B P04271 1/20 0.57
HPGD P15428 1/20 0.57
HPSE Q9Y251 1/20 0.57
RECQL P46063 2/20 0.56
MAPT P10636 1/20 0.56
L3MBTL1 Q9Y468 2/20 0.55
CASP6 P55212 1/20 0.55
TDP1 Q9NUW8 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4230581 0.86 S100B (0.74) CA1CA9KMT2AMEN1ALDH1A1
SCHEMBL11648165 0.85 KMT2A (0.62) KMT2AMEN1ALDH1A1KDM4EPOLB
SCHEMBL7825377 0.85 TYMS (0.71) CA12CA1CA9KMT2AMEN1
SCHEMBL29549557 0.85 TYMS (0.71) CA12CA1CA9KMT2AMEN1
SCHEMBL14172750 0.84 KMT2A (0.72) CA12CA9KMT2AMEN1ALDH1A1
SCHEMBL5012357 0.82 HSD17B10 (0.66) CA12CA1CA9KMT2AMEN1
SCHEMBL9458520 0.82 TDP1 (0.77) CA1CA9KMT2AMEN1ALDH1A1
SCHEMBL30725837 0.82 ESR1 (0.72) KMT2AMEN1ALDH1A1KDM4EPOLB
SCHEMBL29172477 0.82 ESR1 (0.72) KMT2AMEN1ALDH1A1KDM4EPOLB
SCHEMBL481632 0.81 CA1 (0.67) CA12CA1CA9KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US claimed
EP-1465935-B1 PIGMENT COMPOSITIONS WITH MODIFIED ATRP COPOLYMER DISPERSANTS BASF SE (DE) 2016-09-07 EP disclosed
EP-2411437-B9 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK CHEMIE GMBH (DE) 2013-07-31 EP disclosed
EP-2411437-B1 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK CHEMIE GMBH (DE) 2013-05-08 EP disclosed
EP-1611197-B1 LIGHT STABILISING POLYMER DISPERSANTS IN PIGMENT DISPERSIONS BASF SE (DE) 2012-03-21 EP disclosed
US-20120029104-A1 COMPOSITION COMPRISING STABLE POLYOL MIXTURES BYK-CHEMIE GMBH (DE) 2012-02-02 US disclosed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-20060229407-A1 Light stabilising polymer dispersants in pigment dispersions CIBA SPECIALTY CHEMICALS CORP. 2006-10-12 US disclosed
US-20060160940-A1 Process for intercalating natural or szynthetic clays with block or comb copolymers CIBA SPECIALTY CHEMICALS CORP. 2006-07-20 US disclosed
US-6849679-B2 Pigment compositions with modified block copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-02-01 US disclosed