Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094232 | 0.85 | TDP1 (0.50) | SIRT3TDP1KDM4EHTTF7 | |
| SCHEMBL3932429 | 0.83 | KDM4C (0.48) | SIRT3TDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL9017978 | 0.81 | SIRT3 (0.59) | SIRT3TDP1KDM4EHTTF7 | |
| SCHEMBL6215853 | 0.81 | SIRT3 (0.59) | SIRT3TDP1KDM4EHTTF7 | |
| SCHEMBL19052362 | 0.81 | TDP1 (0.38) | SIRT3TDP1KDM4EALDH1A1MEN1 | |
| SCHEMBL1330970 | 0.80 | TDP1 (0.67) | SIRT3TDP1KDM4EHTTF7 | |
| SCHEMBL1687197 | 0.80 | TDP1 (0.67) | SIRT3TDP1KDM4EHTTF7 | |
| SCHEMBL16344275 | 0.77 | KDM4E (0.54) | KDM4EHTTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL16466448 | 0.77 | TDP1 (0.50) | SIRT3TDP1KDM4EHTTF7 | |
| SCHEMBL27598612 | 0.76 | SIRT3 (0.42) | SIRT3TDP1KDM4EHTTF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317105-B2 | Preparation of 4-haloalkylnicotinamides | BAYER CROPSCIENCE AG (DE) | 2008-01-08 | — | — | US | disclosed |
| CN-1310888-C | Method for producing 4-haloalkyl nicotinic acid amides | BAYER CROPSCIENCE GMBH (DE) | 2007-04-18 | — | — | CN | disclosed |
| US-20060100217-A9 | Preparation of 4-haloalkylnicotinamides | PAZENOK SERGIY | 2006-05-11 | — | — | US | disclosed |
| CN-1656074-A | Method for producing 4-haloalkyl nicotinic acid amides | BAYER CROPSCIENCE GMBH (DE) | 2005-08-17 | — | — | CN | disclosed |
| EP-1511731-A1 | METHOD FOR PRODUCING 4-HALOALKYL NICOTINIC ACID AMIDES | Bayer CropScience GmbH (DE) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003099791-A1 | METHOD FOR PRODUCING 4-HALOALKYL NICOTINIC ACID AMIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-12-04 | — | — | WO | disclosed |
| CN-1044233-C | Amide compounds and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA (JP) | 1999-07-21 | — | — | CN | disclosed |
| EP-0580374-B1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-5360806-A | Insecticides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| CN-1081670-A | Amide compound and salt thereof, their manufacturing process and pesticide composition thereof | ISHIHARA SANGYO KAISHA (JP) | 1994-02-09 | — | — | CN | disclosed |
| EP-0580374-A1 | Pyridine amides and their salts, processes for their production and pesticidal compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1994-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100217-A9 | Preparation of 4-haloalkylnicotinamides | CBR3, CBR1, POR | SIRT3 1339/4885TDP1 4590/4885KDM4E 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.