Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752477 | 0.82 | TRPA1 (0.36) | TRPA1 | |
| SCHEMBL1177457 | 0.73 | CYP3A4 (0.35) | — | |
| SCHEMBL4821733 | 0.73 | CYP1A2 (0.35) | — | |
| SCHEMBL4168846 | 0.68 | CYP3A4 (0.33) | — | |
| SCHEMBL21797450 | 0.67 | PIM1 (0.38) | — | |
| SCHEMBL2863 | 0.64 | — | — | |
| SCHEMBL10588380 | 0.64 | — | — | |
| SCHEMBL5712063 | 0.62 | TRPA1 (0.30) | TRPA1 | |
| SCHEMBL5840553 | 0.61 | ALDH1A1 (0.34) | — | |
| SCHEMBL28443493 | 0.61 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |
| CN-1784387-A | Novel benzimidazole derivatives | ASTRAZENECA AB (SE) | 2006-06-07 | — | — | CN | disclosed |