SCHEMBL4818463

SCHEMBL4818463

C1=c2cc3c(cc2-c2ccccc21)=Cc1ccccc1-3

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 2/20 0.34
CDC25A P30304 1/20 0.34
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
BCHE P06276 1/20 0.31
POLB P06746 1/20 0.31
PTPRC P08575 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
PKM P14618 1/20 0.31
IDO1 P14902 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
PTPN1 P18031 1/20 0.31
ACHE P22303 1/20 0.31
CES1 P23141 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4851502 0.85 ALDH1A1 (0.39) MEN1KMT2AALDH1A1LMNAPOLB
SCHEMBL3444764 0.80 MEN1 (0.48) CDC25BCDC25AMEN1KMT2AKDM4E
SCHEMBL22130438 0.79 ABCG2 (0.33)
SCHEMBL22371934 0.79
SCHEMBL31072312 0.79
SCHEMBL5134828 0.78
SCHEMBL440760 0.78 CDC25B (0.38) CDC25BCDC25AMEN1KMT2AKDM4E
SCHEMBL22371940 0.73
SCHEMBL21712108 0.72
SCHEMBL29352607 0.69 CDC25B (0.35) CDC25BCDC25AMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130096336-A1 ALKYNYL-SUBSTITUTED INDENOFLUORENES USEFUL IN ELECTRONIC AND ELECTRO-OPTICAL DEVICES UNIVERSITY OF OREGON 2013-04-18 US claimed
WO-2011159763-A1 ALKYNYL-SUBSTITUTED INDENOFLUORENES USEFUL IN ELECTRONIC AND ELECTRO-OPTICAL DEVICES STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OFOREGON (US) 2011-12-22 WO claimed
US-20240247104-A1 POLYMER COMPOUND, COMPOSITION, ORGANIC FILM, AND ELECTROLUMINESCENT DEVICE COMPRISING POLYMER COMPOUND, AND METHOD OF PREPARING ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-25 US disclosed
US-11453680-B2 Bisbenzofuran-fused indeno[1,2-B]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) MERCK PATENT GMBH (DE) 2022-09-27 US disclosed
US-11258017-B2 Semiconducting compositions comprising semiconducting polymers Wuhan Xinqu Chuangrou Optoelectronics Technology Co., Ltd (CN) 2022-02-22 US disclosed
EP-3544985-A1 BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) Merck Patent GmbH (DE) 2019-10-02 EP disclosed
US-20190131533-A1 SEMICONDUCTING COMPOSITIONS COMPRISING SEMICONDUCTING POLYMERS SILVERRAY LTD. (GB) 2019-05-02 US disclosed
US-10156788-B2 Resist underlayer film composition, patterning process, and compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-12-18 US disclosed
WO-2018095940-A1 BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2018-05-31 WO disclosed
CN-107915661-A Organic semiconductor compound 默克专利股份有限公司 2018-04-17 CN disclosed
US-9876182-B2 Thieno-containing compounds and processes and uses thereof UNIVERSITY OF OREGON (US) 2018-01-23 US disclosed
US-7442760-B2 Electroactive polymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-28 US disclosed
EP-1966842-A2 LIGHTING ELEMENTS, DEVICES AND METHODS Aldred, Matthew, P. (GB) 2008-09-10 EP disclosed
US-20080026135-A1 ELECTRON TRANSPORT AGENTS FOR ORGANIC ELECTRONIC DEVICES 3M INNOVATIVE PROPERTIES COMPANY 2008-01-31 US disclosed
US-7271406-B2 Electron transport agents for organic electronic devices 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-09-18 US disclosed
WO-2007064721-A2 LIGHTING ELEMENTS, DEVICES AND METHODS ALDRED MATTHEW P (GB) 2007-06-07 WO disclosed
US-7094902-B2 Electroactive polymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-08-22 US disclosed
US-20060155106-A1 ELECTROACTIVE POLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2006-07-13 US disclosed
US-20040214036-A1 Electron transport agents for organic electronic devices 3M INNOVATIVE PROPERTIES COMPANY 2004-10-28 US disclosed
US-20040062930-A1 Electroactive polymers 3M INNOVATIVE PROPERTIES COMPANY 2004-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10156788-B2 Resist underlayer film composition, patterning process, and compound PARG, INTS9, PRDM9 CDC25B 3787/4885CDC25A 4126/4885MEN1 2359/4885
US-11258017-B2 Semiconducting compositions comprising semiconducting polymers PARG, PUF60, PARN CDC25B 2124/4885CDC25A 1474/4885MEN1 1661/4885
US-11453680-B2 Bisbenzofuran-fused indeno[1,2-B]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) OCIAD2, OCIAD1, JUND CDC25B 2538/4885CDC25A 4051/4885MEN1 3856/4885
US-20190131533-A1 SEMICONDUCTING COMPOSITIONS COMPRISING SEMICONDUCTING POLYMERS PARG, PUF60, PARN CDC25B 2124/4885CDC25A 1474/4885MEN1 1661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.