Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4820463 | 0.91 | CTSK (0.39) | CTSKCYP3A4TSHRCYP2C19HDAC6 | |
| SCHEMBL4819399 | 0.91 | CTSK (0.39) | CTSKCYP3A4TSHRCYP2C19HDAC6 | |
| SCHEMBL4819388 | 0.91 | CTSK (0.39) | CTSKCYP3A4TSHRCYP2C19HDAC6 | |
| SCHEMBL25085825 | 0.85 | CTSK (0.36) | CTSKHDAC6HDAC1HDAC2L3MBTL1 | |
| SCHEMBL31038369 | 0.84 | CYP3A4 (0.38) | CTSKCYP3A4TSHRCYP2C19HDAC6 | |
| SCHEMBL6339385 | 0.81 | CTSK (0.38) | CTSKTSHRCYP2C19HDAC6HDAC1 | |
| SCHEMBL15866143 | 0.81 | CTSK (0.40) | CTSKHDAC6HDAC1HDAC2PDK2 | |
| SCHEMBL754325 | 0.81 | CTSK (0.37) | CTSKHDAC6HDAC1HDAC2L3MBTL1 | |
| SCHEMBL6327607 | 0.80 | GPR88 (0.36) | CTSKHDAC6HDAC1HDAC2PDK2 | |
| SCHEMBL23572548 | 0.78 | CTSK (0.38) | CTSKHDAC6HDAC1HDAC2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240270736-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-08-15 | — | — | US | disclosed |
| US-7365174-B2 | Azalide and azalactam derivatives and method for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-04-29 | — | — | US | disclosed |
| US-20070042974-A1 | Nozel azalide and azalactam derivatives and method for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1661904-A1 | NOVEL AZALIDE AND AZALACTAM DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2006-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240270736-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | TP53, HRAS, KRAS | CTSK 2352/4885CYP3A4 4030/4885TSHR 1647/4885 |
| US-20070042974-A1 | Nozel azalide and azalactam derivatives and method for producing the same | BCL6, NR4A1, NR4A2 | CTSK 4729/4885CYP3A4 297/4885TSHR 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.