SCHEMBL4818943

SCHEMBL4818943

C=C(C(N)=O)C(C)(c1ccc(Cl)cc1)S(=O)(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
TSHR P16473 2/20 0.39
MAPT P10636 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
POLB P06746 1/20 0.38
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPK1 P28482 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4814830 0.87 ALDH1A1 (0.39) KMT2AMEN1MAPTCYP1A2NPC1
SCHEMBL4821452 0.86 CA1 (0.39) KMT2AMEN1TSHRMAPTNPC1
SCHEMBL30634938 0.67 CYP1A2 (0.54) KMT2AMEN1TSHRMAPTCYP1A2
SCHEMBL2799510 0.66 KMT2A (0.63) KMT2AMEN1TSHRMAPTCYP1A2
SCHEMBL363513 0.65 KMT2A (0.56) KMT2AMEN1TSHRMAPTCYP1A2
SCHEMBL10887061 0.65 KMT2A (0.50) KMT2AMEN1TSHRMAPTCYP1A2
SCHEMBL11845492 0.65 MAP4K4 (0.43) KMT2AMEN1MAPTCYP1A2CYP3A4
SCHEMBL1625391 0.64 MEN1 (0.54) KMT2AMEN1TSHRMAPTCYP1A2
Chlorobenzene SCHEMBL27726786 0.64 TSHR (0.50) KMT2AMEN1TSHRMAPTCYP1A2
SCHEMBL9399853 0.64 TDP1 (0.36) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323282-B2 Dry toner, method for producing dry toner, and method for forming an image CANON KABUSHIKI KAISHA (JP) 2008-01-29 US disclosed
US-20070231729-A1 DRY TONER, METHOD FOR PRODUCING DRY TONER, AND METHOD FOR FORMING AN IMAGE CANON KABUSHIKI KAISHA (JP) 2007-10-04 US disclosed
US-7252917-B2 Dry toner, method for producing dry toner, and method for forming an image CANON KABUSHIKI KAISHA (JP) 2007-08-07 US disclosed
US-20040191661-A1 Dry toner, method for producing dry toner, and method for forming an image CANON KABUSHIKI KAISHA (JP) 2004-09-30 US disclosed