SCHEMBL481947

SCHEMBL481947

CC(C)(C)OC(=O)NCc1ccncc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.58
NAMPT P43490 2/20 0.57
CYP17A1 P05093 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.54
NR1H4 Q96RI1 1/20 0.52
HTT P42858 1/20 0.50
CYP3A4 P08684 1/20 0.50
GAA P10253 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
EPHX1 P07099 1/20 0.48
LMNA P02545 2/20 0.48
POLB P06746 1/20 0.48
MAPK1 P28482 2/20 0.48
MAPT P10636 1/20 0.48
ALDH1A1 P00352 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12346711 0.94 NAMPT (0.56) RAB9ANAMPTCYP17A1L3MBTL1NR1H4
SCHEMBL506891 0.91 CYP17A1 (0.61) RAB9ANAMPTCYP17A1L3MBTL1NR1H4
SCHEMBL5459163 0.90 CYP17A1 (0.57) RAB9ANAMPTCYP17A1L3MBTL1NR1H4
SCHEMBL3180689 0.88 L3MBTL1 (0.61) NAMPTL3MBTL1GAAMAPT
SCHEMBL5479565 0.86 CYP17A1 (0.50) RAB9ANAMPTCYP17A1L3MBTL1NR1H4
SCHEMBL2024124 0.84 CYP17A1 (0.53) RAB9ANAMPTCYP17A1HTTCYP3A4
SCHEMBL17963188 0.84 CYP17A1 (0.53) RAB9ANAMPTCYP17A1L3MBTL1NR1H4
SCHEMBL1438618 0.84 NAMPT (0.75) NAMPTCYP17A1L3MBTL1LMNAMAPT
SCHEMBL3838871 0.83 CA12 (0.63) RAB9ANAMPTL3MBTL1SMN1; SMN2LMNA
SCHEMBL16630327 0.83 NAMPT (0.51) RAB9ANAMPTCYP17A1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109192517-A A kind of quasi-solid electrolyte and preparation method thereof based on cogelled dose of multicomponent is applied with it 中国科学院合肥物质科学研究院 2019-01-11 CN claimed
CN-103779092-A Multicomponent supramolecular gel electrolyte, preparation method and application thereof INST PLASMA PHYSICS CAS 2014-05-07 CN claimed
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS REMEDY PLAN, INC. (US) 2026-05-07 US disclosed
US-12522587-B2 Cancer treatments targeting cancer stem cells REMEDY PLAN, INC. (US) 2026-01-13 US disclosed
WO-2025045758-A1 ANTIBODY-DRUG CONJUGATES BASED ON MOLECULAR GLUE DEGRADERS AND USES THEREOF MABLINK BIOSCIENCE (FR) 2025-03-06 WO disclosed
WO-2025045761-A1 MOLECULAR GLUE DEGRADERS AND USES THEREOF MABLINK BIOSCIENCE (FR) 2025-03-06 WO disclosed
EP-4512806-A1 MOLECULAR GLUE DEGRADERS AND USES THEREOF Mablink Bioscience (FR) 2025-02-26 EP disclosed
EP-4512427-A1 ANTIBODY-DRUG CONJUGATES BASED ON MOLECULAR GLUE DEGRADERS AND USES THEREOF Mablink Bioscience (FR) 2025-02-26 EP disclosed
US-20240239777-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2024-07-18 US disclosed
US-20230398223-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-12-14 US disclosed
US-11834407-B2 Substituted cyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists HEPTARES THERAPEUTICS LIMITED (GB) 2023-12-05 US disclosed
US-5705487-A PEPTIDE DERIVATIVES ELI LILLY AND COMPANY (US) 1998-01-06 US disclosed
CN-1147205-A antithrombotic agent LILLY CO ELI (US) 1997-04-09 CN disclosed
US-5602253-A STARTING MATERIAL FOR SERINE PROTEASE INHIBITORS AKTIEBOLAGET ASTRA (SE) 1997-02-11 US disclosed
CN-1127509-A Novel peptide derivatives ASTRA AB (SE) 1996-07-24 CN disclosed
EP-0701568-A1 NEW PEPTIDE DERIVATIVES Astra Aktiebolag (SE) 1996-03-20 EP disclosed
EP-0672658-A1 Antithrombotic agents ELI LILLY AND COMPANY (US) 1995-09-20 EP disclosed
WO-1995023609-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1995-09-08 WO disclosed
WO-1994029336-A1 NEW PEPTIDE DERIVATIVES ASTRA AKTIEBOLAG (SE) 1994-12-22 WO disclosed
EP-0609625-A1 Inhibitors of HIV protease useful for the treatment of AIDS ELI LILLY AND COMPANY (US) 1994-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239777-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 RAB9A 4270/4885NAMPT 1694/4885CYP17A1 1927/4885
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS MCL1, MALT1, BCL6 RAB9A 1632/4885NAMPT 3339/4885CYP17A1 968/4885
US-20230398223-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 RAB9A 4270/4885NAMPT 1694/4885CYP17A1 1927/4885
US-11834407-B2 Substituted cyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists CHRM1, CHRM2, CHRM4 RAB9A 1971/4885NAMPT 4217/4885CYP17A1 1287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.