SCHEMBL4819905

SCHEMBL4819905

Brc1cc(Br)c(-c2cccs2)s1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 6/20 0.39
MAPT P10636 4/20 0.39
TDP1 Q9NUW8 2/20 0.39
RAB9A P51151 2/20 0.39
PPARG P37231 1/20 0.39
NCOA2 Q15596 1/20 0.39
NCOA1 Q15788 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
ALDH1A1 P00352 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
HPGD P15428 1/20 0.36
KCNH2 Q12809 1/20 0.36
HDAC1 Q13547 1/20 0.36
RPS6KB2 Q9UBS0 2/20 0.35
LTA4H P09960 2/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1629985 0.84 KDM4E (0.41) MEN1KMT2AKDM4EMAPTTDP1
SCHEMBL1780392 0.82 MEN1 (0.40) MEN1KMT2AKDM4EMAPTTDP1
SCHEMBL28878431 0.81 MEN1 (0.39) MEN1KMT2AKDM4EMAPTTDP1
SCHEMBL8508787 0.77 MEN1 (0.36) MEN1KMT2AKDM4EMAPTTDP1
SCHEMBL29839866 0.77 ERN1 (0.47) MEN1KMT2AKDM4EMAPTTDP1
SCHEMBL31099301 0.77 DPP4 (0.51) MEN1KMT2AKDM4EMAPTTDP1
SCHEMBL29783022 0.77 PGR (0.38) MEN1KMT2AKDM4EMAPTTDP1
SCHEMBL18719426 0.76 MEN1 (0.38) MEN1KMT2AKDM4EMAPTTDP1
SCHEMBL19704634 0.72 SNCA (0.42) MEN1KMT2AKDM4EMAPTRAB9A
SCHEMBL915882 0.72 MAPT (0.40) MEN1KMT2AKDM4EMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850666-A Trithiophene alkyl sulfonic acid polymer, and preparation method and application thereof 中国科学院化学研究所 2023-03-28 CN disclosed
US-7462726-B2 Conjugated thiophene compound comprising perfluorinated and alkylated sidechains, conductive organic thin film containing the compound, and field-effect type organic transistor employing the thin film CANON KABUSHIKI KAISHA (JP) 2008-12-09 US disclosed
US-20060234335-A1 Conjugated thiophene compound, conprising perfluorinated and alkylated sidechains, conductive organic thin film containing the compound, and field-effect type organic transistor employing the thin film CANON KABUSHIKI KAISHA (JP) 2006-10-19 US disclosed
WO-2005070992-A2 CONJUGATED THIOPHENE COMPOUND, CONPRISING PERFLUORINATED AND ALKYLATED SIDECHAINS, CONDUCTIVE ORGANIC THIN FILM CONTAINING THE COMPOUND, AND FIELD-EFFECT TYPE ORGANIC TRANSISTOR EMPLOYING THE THIN FILM CANON KABUSHIKI KAISHA (JP) 2005-08-04 WO disclosed