Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.71 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.71 |
| ▸ | DNPH1 | O43598 | 5/20 | 0.70 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.68 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.68 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.68 |
| ▸ | SRC | P12931 | 2/20 | 0.68 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.68 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.68 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.68 |
| ▸ | LDHA | P00338 | 1/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.68 |
| ▸ | FBP1 | P09467 | 1/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.68 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.68 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216645 | 0.99 | P2RX3 (0.70) | P2RX3P2RX2DNPH1P2RY1TAS1R3 | |
| SCHEMBL25698378 | 0.97 | P2RX3 (0.72) | P2RX3P2RX2DNPH1P2RY1TAS1R3 | |
| SCHEMBL20705924 | 0.97 | P2RX3 (0.72) | P2RX3P2RX2DNPH1P2RY1TAS1R3 | |
| SCHEMBL4820592 | 0.94 | DNPH1 (0.73) | P2RX3P2RX2DNPH1P2RY1TAS1R3 | |
| SCHEMBL15305350 | 0.93 | P2RX3 (0.67) | P2RX3P2RX2DNPH1P2RY1TAS1R3 | |
| SCHEMBL14948866 | 0.93 | P2RX3 (0.66) | P2RX3P2RX2DNPH1P2RY1TAS1R3 | |
| SCHEMBL4208216 | 0.93 | P2RX3 (0.84) | P2RX3P2RX2DNPH1P2RY1SRC | |
| SCHEMBL30853828 | 0.92 | P2RX3 (0.82) | P2RX3P2RX2DNPH1P2RY1TAS1R3 | |
| SCHEMBL8738522 | 0.92 | P2RX3 (0.82) | P2RX3P2RX2DNPH1P2RY1TAS1R3 | |
| SCHEMBL4217929 | 0.92 | P2RX3 (0.82) | P2RX3P2RX2DNPH1P2RY1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040241649-A1 | RNA CONTAINING COENZYMES, BIOTIN, OR FLUOROPHORES, AND METHODS FOR THEIR PREPARATION AND USE | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2004-12-02 | — | — | US | claimed |
| US-7323319-B2 | RNA containing coenzymes, biotin, or fluorophores, and methods for their preparation and use | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2008-01-29 | — | — | US | disclosed |
| US-20040241649-A1 | RNA CONTAINING COENZYMES, BIOTIN, OR FLUOROPHORES, AND METHODS FOR THEIR PREPARATION AND USE | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2004-12-02 | — | — | US | disclosed |