Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.61 |
| ▸ | CNR2 | P34972 | 4/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL699925 | 0.81 | MEN1 (0.71) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL7107935 | 0.81 | ALDH1A1 (0.77) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| Phenylacetohydroxamic Acid SCHEMBL213873 | 0.79 | HDAC8 (1.00) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL4821967 | 0.77 | MEN1 (0.72) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL11242611 | 0.77 | MEN1 (0.65) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL4819267 | 0.77 | MEN1 (0.65) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL15338469 | 0.77 | MEN1 (0.65) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL4823048 | 0.77 | MEN1 (0.65) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL60236 | 0.77 | MEN1 (0.65) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL721245 | 0.77 | MEN1 (0.65) | MEN1KMT2AHDAC8HDAC6EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337536-B1 | CATIONIC GROUP-3 CATALYST SYSTEM | EXXONMOBIL CHEM PATENTS INC (US) | 2012-09-12 | — | — | EP | disclosed |
| US-7390861-B2 | Cationic group-3 catalyst system | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-06-24 | — | — | US | disclosed |
| US-20040033891-A1 | Cationic group-3 catalyst system | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-02-19 | — | — | US | disclosed |
| EP-1337536-A1 | CATIONIC GROUP-3 CATALYST SYSTEM | ExxonMobil Chemical Patents Inc. (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002032909-A1 | CATIONIC GROUP-3 CATALYST SYSTEM | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2002-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040033891-A1 | Cationic group-3 catalyst system | COG3, ORC3, LIG3 | MEN1 1242/4885KMT2A 3711/4885HDAC8 4125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.