Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CALML3 | P27482 | 5/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SDHA | P31040 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760026 | 0.86 | MAOA (0.57) | MAOATSHRCALML3MAOBLMNA | |
| SCHEMBL5738561 | 0.84 | MAOA (0.66) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL4757201 | 0.82 | MAOA (0.61) | MAOATSHRCALML3MAOBLMNA | |
| SCHEMBL5738586 | 0.81 | MAOA (0.52) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL4756731 | 0.78 | MAOA (0.69) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL5764719 | 0.76 | MAOA (0.65) | MAOATSHRCALML3MAOBLMNA | |
| SCHEMBL5739416 | 0.75 | MAOA (0.56) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL4638728 | 0.74 | TSHR (0.57) | MAOATSHRCALML3MAOBLMNA | |
| SCHEMBL4638720 | 0.74 | TSHR (0.57) | MAOATSHRCALML3MAOBLMNA | |
| SCHEMBL5764982 | 0.74 | MAOA (0.62) | MAOATSHRCALML3MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902048-A1 | OXAZOLIDINONE CARBOXAMIDES CONTAINING AZETIDINE AND CYCLOBUTANE AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007004037-A1 | OXAZOLIDINONE CARBOXAMIDES CONTAINING AZETIDINE AND CYCLOBUTANE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-11 | — | — | WO | disclosed |