Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.59 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.58 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NCF1 | P14598 | 2/20 | 0.53 |
| ▸ | TOP2A | P11388 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ACP1 | P24666 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1684021 | 0.85 | SCN9A (1.00) | SCN9AKDM4EALDH1A1HPGDGAA | |
| SCHEMBL27873797 | 0.82 | ALDH1A1 (0.71) | SCN9AKDM4EALDH1A1HPGDGAA | |
| SCHEMBL1090319 | 0.82 | TLR9 (0.67) | KDM4EALDH1A1GAATLR9KMT2A | |
| SCHEMBL6330986 | 0.81 | ALDH1A1 (0.73) | SCN9AKDM4EALDH1A1HPGDGAA | |
| Hydrochloric Acid SCHEMBL6336714 | 0.79 | KDM4E (0.71) | SCN9AKDM4EALDH1A1HPGDGAA | |
| SCHEMBL1289837 | 0.78 | SCN9A (1.00) | SCN9AKDM4EALDH1A1HPGDGAA | |
| SCHEMBL1089104 | 0.75 | MRGPRX1 (0.63) | SCN9AKDM4EALDH1A1HPGDGAA | |
| SCHEMBL27763968 | 0.75 | NUDT1 (1.00) | SCN9AKDM4EALDH1A1HPGDGAA | |
| SCHEMBL29713600 | 0.74 | TLR9 (0.95) | ALDH1A1TLR9KMT2AMEN1TOP2A | |
| SCHEMBL1085391 | 0.74 | TLR9 (0.95) | ALDH1A1TLR9KMT2AMEN1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-7375125-B2 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-6699873-B1 | EATING DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | MC4R, MC5R, MC3R | SCN9A 1679/4885KDM4E 1351/4885ALDH1A1 3912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.