SCHEMBL4821265

SCHEMBL4821265

CC(=O)OC[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H](O)C=O

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.71
ABCB1 P08183 1/20 0.40
POLB P06746 1/20 0.40
MAPK1 P28482 1/20 0.40
USP2 O75604 2/20 0.32
CYP3A4 P08684 2/20 0.32
MAPT P10636 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
RECQL P46063 1/20 0.32
PGD P52209 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18860460 1.00 TDP1 (0.71) TDP1ABCB1POLBMAPK1USP2
SCHEMBL11348630 1.00 TDP1 (0.71) TDP1ABCB1POLBMAPK1USP2
SCHEMBL1534011 1.00 TDP1 (0.71) TDP1ABCB1POLBMAPK1USP2
Bromide SCHEMBL8581006 0.98 TDP1 (0.69) TDP1ABCB1POLBMAPK1USP2
SCHEMBL10598584 0.95 TDP1 (0.68) TDP1ABCB1POLBMAPK1USP2
SCHEMBL5167248 0.89 TDP1 (0.64) TDP1ABCB1POLBMAPK1USP2
SCHEMBL7149374 0.86 TDP1 (0.96) TDP1ABCB1POLBMAPK1MAPT
SCHEMBL2175855 0.86 TDP1 (0.96) TDP1ABCB1POLBMAPK1MAPT
SCHEMBL826717 0.86 TDP1 (0.96) TDP1ABCB1POLBMAPK1MAPT
SCHEMBL270042 0.86 TDP1 (0.96) TDP1ABCB1POLBMAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101203249-A Poly (peptide) as chelating agent: method of manufacture and use UNIV TEXAS (US) 2008-06-18 CN claimed
US-20240335551-A1 FUNCTIONAL MOIETIES AND THEIR USES AND SYNTHETIC PREPARATION OLIX US, INC. 2024-10-10 US disclosed
EP-4341269-A1 FUNCTIONAL MOIETIES AND THEIR USES AND SYNTHETIC PREPARATION Olix US, Inc. (US) 2024-03-27 EP disclosed
WO-2022246195-A1 FUNCTIONAL MOIETIES AND THEIR USES AND SYNTHETIC PREPARATION OLIX US, INC. (US) 2022-11-24 WO disclosed
CN-101203249-A Poly (peptide) as chelating agent: method of manufacture and use UNIV TEXAS (US) 2008-06-18 CN disclosed
US-7335500-B2 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose THE SCRIPPS RESEARCH INSTITUTE (US) 2008-02-26 US disclosed
US-20020068331-A1 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose WONG CHI-HUEY (US) 2002-06-06 US disclosed
EP-0910568-A4 SULFINYL HEXOSE DERIVATIVES USEFUL FOR GLYCOSYLATION UNIV PRINCETON (US) 2002-04-24 EP disclosed
US-6319695-B1 FORMING A GLYCOSIDE BOND BY ETHERIFICATION AND CIRCULATION THE SCRIPPS RESEARCH INSITUTE 2001-11-20 US disclosed
US-6040433-A Sulfinyl hexose derivatives useful for glycosylation THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2000-03-21 US disclosed
EP-0901629-A4 CARBOHYDRATE-BASED LIGAND LIBRARY, ASSAY AND METHOD UNIV PRINCETON (US) 2000-02-02 EP disclosed
EP-0910568-A1 SULFINYL HEXOSE DERIVATIVES USEFUL FOR GLYCOSYLATION PRINCETON UNIVERSITY (US) 1999-04-28 EP disclosed
EP-0901629-A1 CARBOHYDRATE-BASED LIGAND LIBRARY, ASSAY AND METHOD PRINCETON UNIVERSITY (US) 1999-03-17 EP disclosed
EP-0642526-B1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE SCRIPPS RESEARCH INST (US) 1998-12-23 EP disclosed
WO-1997035202-A1 CARBOHYDRATE-BASED LIGAND LIBRARY, ASSAY AND METHOD PRINCETON UNIVERSITY (US) 1997-09-25 WO disclosed
WO-1997034906-A1 SULFINYL HEXOSE DERIVATIVES USEFUL FOR GLYCOSYLATION PRINCETON UNIVERSITY (US) 1997-09-25 WO disclosed
EP-0642526-A4 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE. SCRIPPS RESEARCH INST (US) 1996-04-10 EP disclosed
EP-0642526-A1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE THE SCRIPPS RESEARCH INSTITUTE (US) 1995-03-15 EP disclosed
WO-1993008205-A1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE THE SCRIPPS RESEARCH INSTITUTE (US) 1993-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240335551-A1 FUNCTIONAL MOIETIES AND THEIR USES AND SYNTHETIC PREPARATION FGB, SELP, PTMS TDP1 2764/4885ABCB1 3837/4885POLB 585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.