Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11348630 | 1.00 | TDP1 (0.71) | TDP1ABCB1POLBMAPK1USP2 | |
| SCHEMBL4821265 | 1.00 | TDP1 (0.71) | TDP1ABCB1POLBMAPK1USP2 | |
| SCHEMBL1534011 | 1.00 | TDP1 (0.71) | TDP1ABCB1POLBMAPK1USP2 | |
| Bromide SCHEMBL8581006 | 0.98 | TDP1 (0.69) | TDP1ABCB1POLBMAPK1USP2 | |
| SCHEMBL10598584 | 0.95 | TDP1 (0.68) | TDP1ABCB1POLBMAPK1USP2 | |
| SCHEMBL5167248 | 0.89 | TDP1 (0.64) | TDP1ABCB1POLBMAPK1USP2 | |
| SCHEMBL7149374 | 0.86 | TDP1 (0.96) | TDP1ABCB1POLBMAPK1MAPT | |
| SCHEMBL2175855 | 0.86 | TDP1 (0.96) | TDP1ABCB1POLBMAPK1MAPT | |
| SCHEMBL826717 | 0.86 | TDP1 (0.96) | TDP1ABCB1POLBMAPK1MAPT | |
| SCHEMBL270042 | 0.86 | TDP1 (0.96) | TDP1ABCB1POLBMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640526-B2 | Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-05-05 | — | — | US | claimed |
| EP-3377508-A1 | METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE | Centre National De La Recherche Scientifique (FR) | 2018-09-26 | — | — | EP | claimed |
| EP-3170832-A1 | METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE | Centre National De La Recherche Scientifique (FR) | 2017-05-24 | — | — | EP | claimed |
| US-12576155-B2 | Senolytic and antiinflammatory prodrugs and methods of use thereof | PEKING UNIVERSITY (CN) | 2026-03-17 | — | — | US | disclosed |
| WO-2024036961-A1 | PRODRUG FOR ANTI-AGING RELATED DISEASES AND USE METHOD THEREFOR | 北京三秀生物医药科技有限公司 | 2024-02-22 | — | — | WO | disclosed |
| CN-114341148-B | Anti-aging and anti-inflammatory prodrugs and methods of use thereof | 北京大学 | 2024-01-09 | — | — | CN | disclosed |
| US-20220362387-A1 | SENOLYTIC AND ANTIINFLAMMATORY PRODRUGS AND METHODS OF USE THEREOF | PEKING UNIVERSITY (CN) | 2022-11-17 | — | — | US | disclosed |
| CN-114341148-A | Anti-aging and anti-inflammatory prodrugs and methods of use thereof | 北京大学 | 2022-04-12 | — | — | CN | disclosed |
| WO-2021057840-A1 | SENOLYTIC AND ANTIINFLAMMATORY PRODRUGS AND METHODS OF USE THEREOF | PEKING UNIVERSITY (CN) | 2021-04-01 | — | — | WO | disclosed |
| WO-2021057061-A1 | SENOLYTIC AND ANTIINFLAMMATORY PRODRUGS AND METHODS OF USE THEREOF | PEKING UNIVERSITY (CN) | 2021-04-01 | — | — | WO | disclosed |
| WO-2021056270-A1 | SENOLYTIC PRODRUGS AND METHODS OF USE THEREOF | PEKING UNIVERSITY (CN) | 2021-04-01 | — | — | WO | disclosed |
| WO-2021056996-A1 | SENOLYTIC AND ANTIINFLAMMATORY PRODRUGS AND METHODS OF USE THEREOF | PEKING UNIVERSITY (CN) | 2021-04-01 | — | — | WO | disclosed |
| EP-3377508-A1 | METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE | Centre National De La Recherche Scientifique (FR) | 2018-09-26 | — | — | EP | disclosed |
| EP-3377508-A1 | METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE | Centre National De La Recherche Scientifique (FR) | 2018-09-26 | — | — | EP | disclosed |
| WO-2017085145-A1 | METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-05-26 | — | — | WO | disclosed |
| EP-3170832-A1 | METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE | Centre National De La Recherche Scientifique (FR) | 2017-05-24 | — | — | EP | disclosed |
| EP-3170832-A1 | METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE | Centre National De La Recherche Scientifique (FR) | 2017-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12576155-B2 | Senolytic and antiinflammatory prodrugs and methods of use thereof | GLA, SENP6, GLB1 | TDP1 271/4885ABCB1 4086/4885POLB 928/4885 |
| US-20220362387-A1 | SENOLYTIC AND ANTIINFLAMMATORY PRODRUGS AND METHODS OF USE THEREOF | GLA, SENP6, GLB1 | TDP1 468/4885ABCB1 3577/4885POLB 2429/4885 |
| US-10640526-B2 | Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose | ST6GAL1, B4GALT1, GALNT6 | TDP1 2029/4885ABCB1 4158/4885POLB 2482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.