SCHEMBL482140

SCHEMBL482140

O=c1ccn(-c2ccccc2)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 1.00
DDB1 Q16531 1/20 0.50
CRBN Q96SW2 1/20 0.50
GSK3A P49840 3/20 0.41
GSK3B P49841 3/20 0.41
GAA P10253 3/20 0.41
TSHR P16473 1/20 0.39
MPI P34949 1/20 0.39
MGLL Q99685 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.35
ALOX15 P16050 2/20 0.35
ALOX5 P09917 1/20 0.35
G6PD P11413 1/20 0.35
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482570 0.78 SMN1; SMN2 (0.64) SMN1; SMN2MGLLMEN1KMT2AKDM4E
SCHEMBL11132659 0.78 SMN1; SMN2 (0.64) SMN1; SMN2GAAMGLLNPC1RAB9A
SCHEMBL4544224 0.78 SMN1; SMN2 (0.64) SMN1; SMN2DDB1CRBNGSK3AGSK3B
SCHEMBL6986315 0.78 SMN1; SMN2 (0.64) SMN1; SMN2GSK3AGSK3BGAAMGLL
SCHEMBL481991 0.78 SMN1; SMN2 (0.63) SMN1; SMN2GAAMGLLMEN1KMT2A
SCHEMBL3604652 0.77 SMN1; SMN2 (0.61) SMN1; SMN2GAAMPIMGLLMEN1
SCHEMBL10946408 0.74 SMN1; SMN2 (0.58) SMN1; SMN2GSK3AGSK3BMPI
SCHEMBL10689850 0.71 SMN1; SMN2 (0.55) SMN1; SMN2DDB1CRBNGSK3AGSK3B
SCHEMBL8008688 0.71 SMN1; SMN2 (0.55) SMN1; SMN2DDB1CRBNGAAMEN1
SCHEMBL6632956 0.71 SMN1; SMN2 (0.55) SMN1; SMN2MGLLMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117822072-A Tin-silver-copper alloy electroplating solution and electroplating method for wafer-level bump interconnection 大连理工大学 2024-04-05 CN claimed
CN-115947736-A Method for synthesizing succinimide condensed cinnoline compound by spiro rearrangement 河南师范大学 2023-04-11 CN claimed
CN-108251063-B High-performance composite phase-change material and preparation method thereof 有研工程技术研究院有限公司 2021-05-11 CN claimed
EP-2562294-B1 PLATING BATH AND METHOD ROHM & HAAS ELECT MAT (US) 2019-09-25 EP claimed
CN-102732918-B A kind of gold-tin eutectic solder (AuSn20) electroplate liquid and preparation method 广州天极电子科技有限公司 2018-09-07 CN claimed
CN-103592386-B A kind of method of monose and disaccharides and preparation method of derivative reagent of detecting OCEAN UNIVERSITY OF CHINA (CN) 2016-05-11 CN claimed
CN-103698425-B A kind of chemical degradation method obtains and detects the method for biogenetic derivation glycosaminoglycan disaccharides OCEAN UNIVERSITY OF CHINA (CN) 2015-08-26 CN claimed
CN-103698426-B A kind of method obtaining and detect chondroitin sulfate and hyaluronic acid disaccharides of degrading OCEAN UNIVERSITY OF CHINA (CN) 2015-08-05 CN claimed
CN-103713057-B Method for degrading heparan sulfate and detecting heparan sulfate disaccharide composition OCEAN UNIV CHINA 2015-07-08 CN claimed
CN-103675144-B Method for chemically degrading heparin and detecting composition of heparin disaccharide OCEAN UNIV CHINA 2015-06-17 CN claimed
EP-0073875-B1 AZO DYESTUFFS, PROCESS FOR THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1988-09-07 EP claimed
EP-0260561-A2 Process for dyeing leather with dyestuff mixtures BAYER AG (DE) 1988-03-23 EP claimed
US-4720304-A Pigment formulations BASF FARBEN+FASERN AKTIENGESELLSCHAFT (DE) 1988-01-19 US claimed
US-4520095-A STABLE CYAN DYE FOR COLOR DIFFUSION TRANSFER IN SILVER HALIDE EMULSION-CONTAINING FILMS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-05-28 US claimed
US-4420308-A Process for the production of reserve effects on polyester textiles and polyester/cellulose mixed fibre textiles: discharge printing with disperse azo dye with alkyl or alkoxy carbonyl, cyand and hydroxy phenyl group CASSELLA AKTIENGESELLSCHAFT (DE) 1983-12-13 US claimed
EP-0073875-A2 Azo dyestuffs, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1983-03-16 EP claimed
EP-0073876-A1 Process for the production of reserve prints on polyester or polyester cellulose blended textiles CASSELLA Aktiengesellschaft (DE) 1983-03-16 EP claimed
US-4160670-A POLYFUNCTIONAL POLYMERS, METALS OR METAL SULFIDES MITSUBISHI PAPER MILLS, LTD. (JP) 1979-07-10 US claimed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US claimed
US-3973979-A MAGENTA DYES, SILVER HALIDE EMULSIONS AGFA-GEVAERT, A.G. (DT) 1976-08-10 US claimed