Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | PMM2 | O15305 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481991 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2MGLLALDH1A1HPGDALOX5 | |
| SCHEMBL11132659 | 0.77 | SMN1; SMN2 (0.64) | SMN1; SMN2MGLLALDH1A1HPGDALOX5 | |
| SCHEMBL482140 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2MGLLALOX5MEN1KMT2A | |
| SCHEMBL4334784 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1HPGDALKBH5MAPT | |
| SCHEMBL13562672 | 0.75 | ALKBH5 (0.60) | SMN1; SMN2HSP90AA1MGLLL3MBTL1ALDH1A1 | |
| SCHEMBL14685529 | 0.75 | CRBN (0.65) | SMN1; SMN2HSP90AA1MGLLL3MBTL1ALDH1A1 | |
| SCHEMBL11482502 | 0.75 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1ALDH1A1HPGDMAPT | |
| SCHEMBL15717334 | 0.72 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1HPGDALKBH5MAPT | |
| SCHEMBL6535778 | 0.70 | HSP90AA1 (0.52) | HSP90AA1MGLLL3MBTL1ALDH1A1HPGD | |
| SCHEMBL3856173 | 0.70 | ALDH1A1 (0.66) | SMN1; SMN2HSP90AA1MGLLL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828159-A1 | STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |
| US-20100056505-A1 | Substituted Pyrazalones | BIOGEN IDEC MA INC. | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056505-A1 | Substituted Pyrazalones | ACVR1, ACVRL1, TGFBR1 | SMN1; SMN2 4777/4885HSP90AA1 4626/4885MGLL 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.