Sugi Predict

Sugi Predict / Compounds / SCHEMBL482570

SCHEMBL482570

SCHEMBL482570

O=c1ccn(-c2ccc(Cl)cc2)[nH]1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.64
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ HTT P42858 2/20 0.43
▸ HPGD P15428 2/20 0.43
▸ MGLL Q99685 1/20 0.42
▸ ALOX5 P09917 2/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ ATM Q13315 1/20 0.39
▸ ALKBH5 Q6P6C2 1/20 0.39
▸ ELANE P08246 1/20 0.38
▸ MAPT P10636 2/20 0.38
▸ POLB P06746 2/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ GPR84 Q9NQS5 1/20 0.37
▸ APOBEC3G Q9HC16 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ HTR3E A5X5Y0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6986315 0.79 SMN1; SMN2 (0.64) SMN1; SMN2MEN1KMT2AALDH1A1HTT
SCHEMBL11132659 0.79 SMN1; SMN2 (0.64) SMN1; SMN2ALDH1A1HPGDMGLLALOX5
SCHEMBL481991 0.79 SMN1; SMN2 (0.63) SMN1; SMN2MEN1KMT2AALDH1A1HTT
SCHEMBL482140 0.78 SMN1; SMN2 (1.00) SMN1; SMN2MEN1KMT2AMGLLALOX5
SCHEMBL30278609 0.75 SMN1; SMN2 (0.58) SMN1; SMN2ALDH1A1ELANEPOLBKDM4E
SCHEMBL23273657 0.73 ALOX12 (0.44) SMN1; SMN2MEN1KMT2AALDH1A1HTT
SCHEMBL8663896 0.73 SMN1; SMN2 (0.43) SMN1; SMN2MEN1KMT2AALDH1A1HTT
SCHEMBL19120983 0.71 SMN1; SMN2 (0.53) SMN1; SMN2MEN1KMT2AALDH1A1HPGD
SCHEMBL4334784 0.71 SMN1; SMN2 (0.53) SMN1; SMN2MEN1KMT2AALDH1A1HTT
SCHEMBL28744936 0.69 CRBN (0.66) SMN1; SMN2MEN1KMT2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118142533-B Active carbon supported multi-metal catalyst, preparation method and application thereof, and preparation method of 1- (4-chlorophenyl) -3-pyrazolol EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2026-05-26 — — CN claimed
CN-119684213-A Preparation method and control method of 2- [ (N-p-chlorophenyl) -3-pyrazoloxymethyl ] nitrobenzene isomer 江苏丰山生化科技有限公司 2025-03-25 — — CN claimed
CN-114181151-B Oxidation method of 1- (4-chlorophenyl) -3-pyrazolol 湖南化工研究院有限公司 2024-03-29 — — CN claimed
CN-110105287-B Synthesis process of pyraclostrobin 江苏禾本生化有限公司 2022-04-26 — — CN claimed
CN-110105287-A A kind of synthesis technology of pyraclostrobin 江苏禾本生化有限公司 2019-08-09 — — CN claimed
CN-105111148-A 2-[(N-para-chlorophenyl)-3-pyrazole oxymethyl]nitrobenzene and preparation method therefor and application thereof ANHUI COSTAR BIO CHEMICAL CO LTD 2015-12-02 — — CN claimed
CN-104592117-A Synthesis method of pyraclostrobin ANHUI COSTAR BIO CHEMICAL CO LTD 2015-05-06 — — CN claimed
US-20250215012-A1 IKZF2 DEGRADERS AND USES THEREOF UNIV MICHIGAN (US) 2025-07-03 — — US disclosed
CN-119800380-A Electrolytic synthesis method of pyrazolone compound intermediate 浙江工业大学 2025-04-11 — — CN disclosed
CN-119731179-A IKZF2 degradation agent and application thereof 密歇根大学董事会 2025-03-28 — — CN disclosed
CN-119684213-A Preparation method and control method of 2- [ (N-p-chlorophenyl) -3-pyrazoloxymethyl ] nitrobenzene isomer 江苏丰山生化科技有限公司 2025-03-25 — — CN disclosed
EP-4499649-A1 IKZF2 DEGRADERS AND USES THEREOF Regents of the University of Michigan (US) 2025-02-05 — — EP disclosed
CN-119318926-A Continuous production system and production method of 1- (4-chlorophenyl) -3-pyrazolol 中国石油大学(华东) 2025-01-17 — — CN disclosed
WO-2007027959-A1 NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS JANSSEN PHARMACEUTICA N.V. (BE) 2007-03-08 — — WO disclosed
US-20070049556-A1 NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS JANSSEN PHARMACEUTICA N.V. (BE) 2007-03-01 — — US disclosed
EP-1485167-A1 1,2-DIHYDROPYRAZOL-3-ONES AS CYTOKINE MEDIATORS The Procter & Gamble Company (US) 2004-12-15 — — EP disclosed
WO-2003080184-A1 1,2-DIHYDROPYRAZOL-3-ONES AS CYTOKINE MEDIATORS THE PROCTER & GAMBLE COMPANY (US) 2003-10-02 — — WO disclosed
US-6589974-B1 For controlling harmful organisms multistage reaction BAYER AKTIENGESELLSCHAFT (DE) 2003-07-08 — — US disclosed
US-20030109702-A1 Fungicides, bactericides BAYER AKTIENGESELLSCHAFT (DE) 2003-06-12 — — US disclosed
US-6562856-B1 The invention relates to novel pyrazolyl benzyl ethers, to a process for their preparation and to their use for controlling harmful organisms, bactericides and fungicide BAYER AKTIENGESELLSCHAFT (DE) 2003-05-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215012-A1 IKZF2 DEGRADERS AND USES THEREOF IKZF1, IKZF2, IKZF3 SMN1; SMN2 2807/4885MEN1 4085/4885KMT2A 444/4885
US-20030109702-A1 Fungicides, bactericides BTD, CYP51A1, DDT SMN1; SMN2 3249/4885MEN1 1132/4885KMT2A 2854/4885
US-20070049556-A1 NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS KCNJ2, KCNN1, KCNN3 SMN1; SMN2 1599/4885MEN1 3815/4885KMT2A 1443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.