Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 12/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11963202 | 0.82 | TRPV4 (0.50) | TRPV4DAOKCNJ1KCNH2CYP11B1 | |
| SCHEMBL9240972 | 0.81 | HSD17B10 (0.49) | TRPV4DAOKCNJ1KCNH2CYP11B1 | |
| SCHEMBL6561624 | 0.80 | TRPV4 (0.52) | TRPV4DAOKCNJ1KCNH2CYP11B1 | |
| SCHEMBL4825303 | 0.79 | TRPV4 (0.50) | TRPV4DAOKCNJ1KCNH2CYP11B1 | |
| SCHEMBL6411198 | 0.79 | TRPV4 (0.50) | TRPV4DAOKCNJ1KCNH2CYP11B1 | |
| SCHEMBL13548285 | 0.78 | TRPV4 (0.53) | TRPV4DAOKCNJ1KCNH2CYP11B1 | |
| SCHEMBL10536579 | 0.76 | DAO (0.38) | TRPV4DAOKCNJ1KCNH2KDM1A | |
| SCHEMBL6564705 | 0.76 | TRPV4 (0.55) | TRPV4DAOKCNJ1KCNH2CYP11B1 | |
| SCHEMBL8154750 | 0.76 | TSHR (0.51) | TRPV4DAOKCNJ1CYP11B1CYP11B2 | |
| SCHEMBL7994529 | 0.75 | TRPV4 (0.46) | TRPV4DAOKCNJ1KCNH2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335405-B2 | Nematic liquid crystal mixtures for use in bistable display devices | NEMOPTIC (FR) | 2008-02-26 | — | — | US | claimed |
| US-20060249708-A1 | Nematic liquid crystal mixtures for use in bistable display devices | CDC PROPRIETE INTELLECTUELLE (FR) | 2006-11-09 | — | — | US | claimed |
| US-7335405-B2 | Nematic liquid crystal mixtures for use in bistable display devices | NEMOPTIC (FR) | 2008-02-26 | — | — | US | disclosed |
| US-20060249708-A1 | Nematic liquid crystal mixtures for use in bistable display devices | CDC PROPRIETE INTELLECTUELLE (FR) | 2006-11-09 | — | — | US | disclosed |