Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 14/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 13/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477145 | 0.79 | CYP11B1 (0.48) | TRPV4CYP11B2CYP11B1KCNJ1 | |
| SCHEMBL9477164 | 0.79 | CYP11B1 (0.48) | TRPV4CYP11B2CYP11B1KCNJ1 | |
| SCHEMBL287322 | 0.78 | TRPV4 (0.53) | TRPV4DAOCYP11B2CYP11B1KCNJ1 | |
| SCHEMBL6564705 | 0.76 | TRPV4 (0.55) | TRPV4DAOCYP11B2CYP11B1KCNJ1 | |
| SCHEMBL6411198 | 0.76 | TRPV4 (0.50) | TRPV4DAOCYP11B2CYP11B1KCNJ1 | |
| SCHEMBL7998375 | 0.76 | KIF11 (0.33) | KCNH2 | |
| SCHEMBL4821602 | 0.75 | TRPV4 (0.46) | TRPV4DAOCYP11B2CYP11B1KCNJ1 | |
| SCHEMBL5316849 | 0.75 | TRPV4 (0.53) | TRPV4DAOCYP11B2CYP11B1KCNJ1 | |
| SCHEMBL13548285 | 0.75 | TRPV4 (0.53) | TRPV4DAOCYP11B2CYP11B1KCNJ1 | |
| Hydrochloric Acid SCHEMBL28803020 | 0.75 | TRPV4 (0.53) | TRPV4DAOCYP11B2CYP11B1KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001051494-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-07-19 | — | — | WO | disclosed |