Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.35 |
| ▸ | CX3CR1 | P49238 | 4/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863727 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL4823294 | 0.82 | IDO1 (0.37) | ALDH1A1CYP3A4CXCR2CX3CR1ACE | |
| Hydrochloric Acid SCHEMBL3858550 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL4820948 | 0.79 | MAPT (0.46) | METAP2ACE | |
| SCHEMBL4824656 | 0.78 | ELANE (0.48) | METAP2ACE | |
| SCHEMBL4825569 | 0.78 | CYP1A2 (0.41) | ALDH1A1CXCR2CX3CR1METAP2ACE | |
| SCHEMBL4859768 | 0.76 | ALDH1A1 (0.44) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL4854335 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL4854433 | 0.73 | ALDH1A1 (0.44) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL4823221 | 0.72 | CYP3A4 (0.38) | ALDH1A1CYP3A4THRBALOX15RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7347879-B2 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | L'Oreál, S.A. (FR) | 2008-03-25 | — | — | US | claimed |
| US-20060005321-A1 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | claimed |
| EP-1568687-A1 | Sulphur-containing secondary para-Phenylenediamines, dying composition containing such para-phenylenediamines and methods using this composition and use | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| US-7347879-B2 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | L'Oreál, S.A. (FR) | 2008-03-25 | — | — | US | disclosed |
| US-7347879-B2 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | L'Oreál, S.A. (FR) | 2008-03-25 | — | — | US | disclosed |
| US-7347879-B2 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | L'Oreál, S.A. (FR) | 2008-03-25 | — | — | US | disclosed |
| US-20060005321-A1 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060005321-A1 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | KRT18, CDC73, DSG1 | ALDH1A1 1148/4885CYP3A4 3389/4885THRB 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.