Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122502 | 0.85 | NISCH (0.51) | NISCHPDCD1LG2CD274 | |
| SCHEMBL4823981 | 0.82 | NISCH (0.56) | NISCHLMNA | |
| SCHEMBL4815718 | 0.79 | NISCH (0.54) | NISCH | |
| Pamoic Acid SCHEMBL9123814 | 0.78 | GPR35 (0.50) | NISCH | |
| SCHEMBL8202723 | 0.77 | NISCH (0.75) | NISCHLMNARECQL | |
| SCHEMBL4813698 | 0.77 | NISCH (0.58) | NISCH | |
| SCHEMBL2949149 | 0.76 | NISCH (0.62) | NISCH | |
| Formic Acid SCHEMBL4904523 | 0.76 | NISCH (0.49) | NISCHLMNA | |
| SCHEMBL4815704 | 0.74 | NISCH (0.70) | NISCHLMNAPDCD1LG2CD274 | |
| SCHEMBL6747069 | 0.74 | NISCH (0.47) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516234-B1 | Phenoxyphenyl derivatives | AKZO NOBEL NV (NL) | 1995-09-13 | — | — | EP | claimed |
| US-5190965-A | Treatment of depression | AKZO N.V. (NL) | 1993-03-02 | — | — | US | claimed |
| EP-0516234-A1 | Phenoxyphenyl derivatives | Akzo Nobel N.V. (NL) | 1992-12-02 | — | — | EP | claimed |
| JP-5148197-A | — | — | None | — | — | JP | disclosed |
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-7375125-B2 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375125-B2 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375125-B2 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| EP-0516234-B1 | Phenoxyphenyl derivatives | AKZO NOBEL NV (NL) | 1995-09-13 | — | — | EP | disclosed |
| US-5430063-A | Antidepressants | AKZO N.V. (NL) | 1995-07-04 | — | — | US | disclosed |
| JP-H05148197-A | PHENOXYPHENYL DERIVATIVE | AKZO NV | 1993-06-15 | — | — | JP | disclosed |
| US-5190965-A | Treatment of depression | AKZO N.V. (NL) | 1993-03-02 | — | — | US | disclosed |
| EP-0516234-A1 | Phenoxyphenyl derivatives | Akzo Nobel N.V. (NL) | 1992-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | MC4R, MC5R, MC3R | NISCH 1934/4885LMNA 2506/4885RECQL 3420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.