Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 8/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194068 | 0.85 | NISCH (0.77) | NISCH | |
| SCHEMBL9579892 | 0.84 | NISCH (0.81) | NISCH | |
| SCHEMBL8197935 | 0.83 | NISCH (0.75) | NISCH | |
| SCHEMBL8195009 | 0.82 | NISCH (0.74) | NISCHLMNARECQL | |
| SCHEMBL523059 | 0.82 | LMNA (0.96) | NISCHLMNARECQL | |
| SCHEMBL8188355 | 0.80 | LMNA (0.92) | NISCHLMNARECQL | |
| SCHEMBL8202988 | 0.80 | NISCH (0.71) | NISCH | |
| SCHEMBL8200536 | 0.80 | NISCH (0.71) | NISCH | |
| SCHEMBL8189633 | 0.80 | NISCH (0.71) | NISCH | |
| SCHEMBL8239326 | 0.80 | NISCH (0.57) | NISCHLMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |