Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Crotonic Acid SCHEMBL4822259 | 1.00 | HCAR2 (0.48) | HCAR2TSHRTP53EGLN1EGLN3 | |
| Maleic Acid SCHEMBL2833047 | 0.87 | HCAR2 (0.61) | HCAR2TSHRTP53EGLN1EGLN3 | |
| Fumaric Acid SCHEMBL11884545 | 0.87 | HCAR2 (0.61) | HCAR2TSHRTP53EGLN1EGLN3 | |
| Fumaric Acid SCHEMBL6291284 | 0.87 | HCAR2 (0.61) | HCAR2TSHRTP53EGLN1EGLN3 | |
| Maleic Acid SCHEMBL27742359 | 0.84 | HCAR2 (0.58) | HCAR2TSHRTP53EGLN1EGLN3 | |
| Sorbic Acid SCHEMBL6851012 | 0.84 | HCAR2 (0.43) | HCAR2TSHRTP53EGLN1EGLN3 | |
| Crotonic Acid SCHEMBL27718105 | 0.84 | — | — | |
| Maleic Acid SCHEMBL19900431 | 0.82 | HCAR2 (0.56) | HCAR2TSHRTP53EGLN1EGLN3 | |
| Crotonic Acid SCHEMBL3260978 | 0.81 | — | — | |
| Crotonic Acid SCHEMBL5706213 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399478-B2 | Cosmetic, pharmaceutical and dermatological products | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2008-07-15 | — | — | US | disclosed |
| US-7297328-B2 | Surfactant-free cosmetic, dermatological and pharmaceutical agents | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2007-11-20 | — | — | US | disclosed |