Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972697 | 0.89 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DADORA1 | |
| SCHEMBL4816797 | 0.89 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL4694446 | 0.87 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4DADORA1 | |
| SCHEMBL973098 | 0.85 | CNR1 (0.48) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL4693580 | 0.81 | CNR1 (0.45) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL17163901 | 0.79 | CNR2 (0.62) | CNR1KDM4ECNR2MAPT | |
| SCHEMBL2869898 | 0.78 | CNR1 (0.61) | CNR1KDM4ECNR2MAPT | |
| SCHEMBL700719 | 0.78 | CNR1 (0.58) | PDE4BCNR1CNR2CYP19A1 | |
| SCHEMBL4910813 | 0.77 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL974512 | 0.77 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7354929-B2 | Cannabinoid receptor ligands and uses thereof | PFIZER INC. (US) | 2008-04-08 | — | — | US | disclosed |
| US-20070105856-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER INC | 2007-05-10 | — | — | US | disclosed |
| US-7141669-B2 | Cannabiniod receptor ligands and uses thereof | PFIZER INC. (US) | 2006-11-28 | — | — | US | disclosed |
| EP-1622902-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | Pfizer Products Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004094417-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2004-11-04 | — | — | WO | disclosed |
| US-20040214838-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105856-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | CNR1, CNR2, GPR18 | PDE4B 2281/4885PDE4A 2206/4885PDE4C 2754/4885 |
| US-20040214838-A1 | Cannabinoid receptor ligands and uses thereof | CNR1, CNR2, GPR18 | PDE4B 2474/4885PDE4A 2332/4885PDE4C 2930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.