Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186644 | 0.89 | PDE4B (0.51) | PDE4BCNR1NPSR1ALDH1A1PDE4A | |
| SCHEMBL972697 | 0.87 | PDE4B (0.49) | PDE4BCNR1NPSR1ALDH1A1LPAR5 | |
| SCHEMBL4822288 | 0.87 | PDE4B (0.48) | PDE4BCNR1NPSR1ALDH1A1LPAR5 | |
| SCHEMBL973098 | 0.83 | CNR1 (0.48) | PDE4BCNR1NPSR1ALDH1A1LPAR5 | |
| SCHEMBL4689130 | 0.81 | PDE4B (0.51) | PDE4BCNR1NPSR1ALDH1A1PDE4A | |
| SCHEMBL4693580 | 0.81 | CNR1 (0.45) | PDE4BCNR1NPSR1ALDH1A1LPAR5 | |
| SCHEMBL5368660 | 0.81 | PDE4B (0.57) | PDE4BNPSR1ALDH1A1PDE4APDE4C | |
| SCHEMBL4187487 | 0.79 | CNR1 (0.59) | CNR1CNR2MAPT | |
| SCHEMBL4693433 | 0.79 | PDE4B (0.55) | PDE4BNPSR1ALDH1A1PDE4APDE4C | |
| SCHEMBL2869898 | 0.77 | CNR1 (0.61) | CNR1CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874779-A1 | ACYLAMINOBICYCLIC HETEROMATIC COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | Pfizer Products Inc. (US) | 2008-01-09 | — | — | EP | disclosed |
| US-20060241100-A1 | Acylaminobicyclic heteroaromatic compounds and uses thereof | PFIZER INC | 2006-10-26 | — | — | US | disclosed |
| WO-2006111849-A1 | ACYLAMINOBICYCLIC HETEROMATIC COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | PFIZER PRODUCTS INC. (US) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241100-A1 | Acylaminobicyclic heteroaromatic compounds and uses thereof | CNR2, CNR1, GPR18 | PDE4B 2817/4885CNR1 2/4885NPSR1 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.