Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 4/20 | 0.42 |
| ▸ | TK1 | P04183 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29286377 | 0.91 | TK1 (0.46) | PNPTK1MAPTALDH1A1HPRT1 | |
| SCHEMBL48362 | 0.85 | TK1 (0.51) | PNPTK1ADORA2BALDH1A1SMN1; SMN2 | |
| SCHEMBL27710751 | 0.85 | ADORA2A (0.52) | TK1ADORA2BALDH1A1KMT2AMEN1 | |
| Guanine SCHEMBL27744184 | 0.84 | PNP (0.54) | PNPTK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28712711 | 0.83 | PNP (0.42) | PNPTK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6703317 | 0.82 | PNP (0.51) | PNPALDH1A1SMN1; SMN2HPRT1KMT2A | |
| SCHEMBL1665132 | 0.82 | TK1 (0.47) | PNPTK1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4592790 | 0.82 | ADORA2A (0.47) | PNPTK1MAPTALDH1A1KMT2A | |
| SCHEMBL48267 | 0.82 | ALDH1A1 (0.45) | PNPTK1ALDH1A1SMN1; SMN2HPRT1 | |
| SCHEMBL7977785 | 0.82 | TK1 (0.64) | PNPTK1HPRT1HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180258474-A1 | METHODS FOR DETERMINING BASE LOCATIONS IN A POLYNUCLEOTIDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-09-13 | — | — | US | claimed |
| EP-1419247-B1 | METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS | DIREVO BIOTECH AG (DE) | 2006-09-20 | — | — | EP | claimed |
| US-20050130142-A1 | Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids | DIREVO BIOTECH AG (DE) | 2005-06-16 | — | — | US | claimed |
| EP-1419247-A2 | METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS | Direvo Biotech AG (DE) | 2004-05-19 | — | — | EP | claimed |
| WO-2003012100-A2 | METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS | DIREVO BIOTECH AG (DE) | 2003-02-13 | — | — | WO | claimed |
| EP-1281757-A1 | Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids | Direvo Biotech AG (DE) | 2003-02-05 | — | — | EP | claimed |
| EP-4665866-A1 | REAGENTS AND METHODS FOR NORMALIZATION | Twist Bioscience Corporation (US) | 2025-12-24 | — | — | EP | disclosed |
| CN-119677866-A | Substrate cleavage for nucleic acid synthesis | 特韦斯特生物科学公司 | 2025-03-21 | — | — | CN | disclosed |
| EP-4504959-A1 | SUBSTRATE CLEAVAGE FOR NUCLEIC ACID SYNTHESIS | Twist Bioscience Corporation (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2024173880-A1 | REAGENTS AND METHODS FOR NORMALIZATION | Twist Bioscience Corporation (US) | 2024-08-22 | — | — | WO | disclosed |
| EP-4402277-A1 | SYNTHESIS OF OLIGONUCLEOTIDES | The University of Manchester (GB) | 2024-07-24 | — | — | EP | disclosed |
| CN-117980494-A | Oligonucleotide synthesis | 曼彻斯特大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-113272442-B | One-pot synthesis of pools of oligonucleotides | DNA斯克瑞普特公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-2028272-A1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | Panasonic Corporation (JP) | 2009-02-25 | — | — | EP | disclosed |
| EP-1419247-B1 | METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS | DIREVO BIOTECH AG (DE) | 2006-09-20 | — | — | EP | disclosed |
| EP-1647592-A1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2006-04-19 | — | — | EP | disclosed |
| US-20050130142-A1 | Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids | DIREVO BIOTECH AG (DE) | 2005-06-16 | — | — | US | disclosed |
| EP-1419247-A2 | METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS | Direvo Biotech AG (DE) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003012100-A2 | METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS | DIREVO BIOTECH AG (DE) | 2003-02-13 | — | — | WO | disclosed |
| EP-1281757-A1 | Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids | Direvo Biotech AG (DE) | 2003-02-05 | — | — | EP | disclosed |