Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2513756 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL5949066 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL6515877 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL2970565 | 0.68 | CYP11B1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL5949027 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL5168251 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL5948542 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL5948728 | 0.63 | — | — | |
| SCHEMBL1453380 | 0.61 | KCNH2 (0.40) | — | |
| SCHEMBL1454519 | 0.60 | HTR2C (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |
| US-6482902-B1 | Catalyst system | TARGOR GMBH (DE) | 2002-11-19 | — | — | US | claimed |
| US-7470460-B2 | a multilayer substrate comprising thermoplastic polymers having a decorative layer composed of a chromed metal on n intermediate layer and a heat-cured layer over the decorative layer; reflectors or insulators of household wares, moldings in the electrical, construction or automotive industry | BASELL POLYOLEFINE GMBH (DE) | 2008-12-30 | — | — | US | disclosed |
| US-7105218-B1 | Cover plate for household devices | BASELL POLYOLEFINE GMBH (DE) | 2006-09-12 | — | — | US | disclosed |
| US-7101940-B2 | Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2006-09-05 | — | — | US | disclosed |
| US-7034173-B2 | Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2006-04-25 | — | — | US | disclosed |
| US-6986936-B2 | Layered composite materials with a decorative layer made from a chromed metal | BASELL POLYDLEFINE GMBH (DE) | 2006-01-17 | — | — | US | disclosed |
| US-6972153-B2 | Resin layer having degree of curing of at least 20% inserted between support and intermediate layer and resin layer having degree of curing of at least 60% is inserted between intermediate layer and heat-cured layer; impact strength | BASELL POLYOLEFINE GMBH (DE) | 2005-12-06 | — | — | US | disclosed |
| US-20050266234-A1 | a multilayer substrate comprising thermoplastic polymers having a decorative layer composed of a chromed metal on n intermediate layer and a heat-cured layer over the decorative layer; reflectors or insulators of household wares, moldings in the electrical, construction or automotive industry | MUELLER KLAUS | 2005-12-01 | — | — | US | disclosed |
| US-6949614-B1 | Catalyst system | BASELL POLYOLEFINE GMBH (DE) | 2005-09-27 | — | — | US | disclosed |
| US-6861384-B2 | Process for preparation of a salt-like chemical compound and its use in catalyst systems for preparing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2005-03-01 | — | — | US | disclosed |
| US-20030144434-A1 | Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins | EQUISTAR CHEMICALS, LP | 2003-07-31 | — | — | US | disclosed |
| US-20030069426-A1 | Saline chemical composition, method for producing the same and the use thereof in catalyst systems for producing polyolefins | SCHOTTEK JORG (DE) | 2003-04-10 | — | — | US | disclosed |
| US-20030013913-A1 | Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins | EQUISTAR CHEMICALS, LP | 2003-01-16 | — | — | US | disclosed |
| US-6494982-B1 | PRODUCING A COMPOSITE MATERIAL WITH AN INTERMEDIATE LAYER MADE FROM A THERMOPLASTIC POLYMER, AN INTERMEDIATE LAYER ARRANGED AND A HEAT-CURED LAYER APPLIED TO THE INTERMEDIATE LAYER, WHERE THE BONDING MATERIAL OF THE INTERMEDIATE LAYER IS A | TARGOR GMBH (DE) | 2002-12-17 | — | — | US | disclosed |
| US-6482902-B1 | Catalyst system | TARGOR GMBH (DE) | 2002-11-19 | — | — | US | disclosed |
| US-6469114-B1 | TO AVOID DEPOSIT FORMATION IN THE REACTOR, SUPPORTED CATALYST SYSTEMS IN WHICH THE METALLOCENE AND/OR THE ALUMINUM COMPOUNDS SERVING AS COCATALYST ARE FIXED ON AN INORGANIC SUPPORT MATERIAL HAVE BEEN PROPOSED | BASELL POLYOLEFINS GMBH (DE) | 2002-10-22 | — | — | US | disclosed |
| US-20010054838-A1 | Frontal part comprising a decorative part | EQUISTAR CHEMICALS, LP | 2001-12-27 | — | — | US | disclosed |
| US-20010033919-A1 | Layered composite materials with a decorative layer made from a chromed metal | EQUISTAR CHEMICALS, LP | 2001-10-25 | — | — | US | disclosed |
| US-20010017301-A1 | Inner container for household devices | LYONDELL CHEMICAL TECHNOLOGY, L.P. | 2001-08-30 | — | — | US | disclosed |