Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2970565

CC1=Cc2ccccc2C1[Si](C)(C)C1C(C)=Cc2ccccc21.[Cl-].[Cl-].[Zr+2]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8860745 0.96 CYP11B1 (0.33) CYP11B1CYP11B2CYP19A1
SCHEMBL29844183 0.96 CYP19A1 (0.32) CYP11B1CYP11B2CYP19A1
SCHEMBL61361 0.96 CYP19A1 (0.32) CYP11B1CYP11B2CYP19A1
SCHEMBL4612462 0.94 CYP19A1 (0.31) CYP11B1CYP11B2CYP19A1
Hydrochloric Acid SCHEMBL7196460 0.92 CYP19A1 (0.30) CYP11B1CYP11B2CYP19A1
SCHEMBL1453940 0.87 GPR3 (0.33)
SCHEMBL7055976 0.86 CYP11B1 (0.33) CYP11B1CYP11B2CYP19A1
SCHEMBL1453690 0.84
SCHEMBL7053946 0.84 CYP19A1 (0.32) CYP11B1CYP11B2CYP19A1
SCHEMBL1822867 0.82 CYP19A1 (0.31) CYP11B1CYP11B2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1995258-B1 Catalyst composition for polymerizing monomers CHEVRON PHILLIPS CHEMICAL CO (US) 2013-08-21 EP claimed
US-7763561-B2 Compositions that can produce polymers CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-07-27 US claimed
US-7601665-B2 Compositions that can produce polymers CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2009-10-13 US claimed
US-20080058199-A1 COMPOSITIONS THAT CAN PRODUCE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 2008-03-06 US claimed
US-6531550-B1 Process for producing polymers PHILLIPS PETROLEUM COMPANY 2003-03-11 US claimed
US-6316553-B1 CONTACTING MONOMER WITH CATALYST WHICH IS IS PRODUCED BY CONTACTING ORGANOMETAL COMPOUND, TREATED SOLID OXIDE COMPOUND, ORGANOALUMINUM COMPOUND TO PRODUCE POLYMER PHILLIPS PETROLEUM COMPANY 2001-11-13 US claimed
US-6300271-B1 OXIDES AND ORGANOALUMINUM COMPOUNDS PHILLIPS PETROLEUM COMPANY 2001-10-09 US claimed
US-6165929-A Compositions that can produce polymers PHILLIPS PETROLEUM COMPANY (US) 2000-12-26 US claimed
WO-1997014727-A1 HOMOGENEOUS METALLOCENE-BASED OLEFIN POLYMERIZATION SYSTEM WITH INCREASED ACTIVITY AMOCO CORPORATION (US) 1997-04-24 WO claimed
US-20100280199-A1 COMPOSITIONS THAT CAN PRODUCE POLYMERS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-11-04 US disclosed
US-7763561-B2 Compositions that can produce polymers CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-07-27 US disclosed
US-7378476-B2 Olefin polymerization process in the presence of a radical generating system INEOS USA LLC (US) 2008-05-27 US disclosed
US-20080058199-A1 COMPOSITIONS THAT CAN PRODUCE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 2008-03-06 US disclosed
US-7247686-B2 Solid cocatalyst component for olefin polymerization and catalyst system thereof BASELL POLYOLEFINE GMBH (DE) 2007-07-24 US disclosed
US-20050009689-A1 Solid cocatalyst component for olefin polymerization and catalyst system thereof SUNALLOMER LTD. (JP) 2005-01-13 US disclosed
US-6316553-B1 CONTACTING MONOMER WITH CATALYST WHICH IS IS PRODUCED BY CONTACTING ORGANOMETAL COMPOUND, TREATED SOLID OXIDE COMPOUND, ORGANOALUMINUM COMPOUND TO PRODUCE POLYMER PHILLIPS PETROLEUM COMPANY 2001-11-13 US disclosed
US-6300271-B1 OXIDES AND ORGANOALUMINUM COMPOUNDS PHILLIPS PETROLEUM COMPANY 2001-10-09 US disclosed
US-6165929-A Compositions that can produce polymers PHILLIPS PETROLEUM COMPANY (US) 2000-12-26 US disclosed
US-5756609-A Homogeneous metallocene-based olefin polymerization system with increased activity AMOCO CORPORATION (US) 1998-05-26 US disclosed
WO-1997014727-A1 HOMOGENEOUS METALLOCENE-BASED OLEFIN POLYMERIZATION SYSTEM WITH INCREASED ACTIVITY AMOCO CORPORATION (US) 1997-04-24 WO disclosed