SCHEMBL4822602

SCHEMBL4822602

CON(C)C(=O)c1c[c]cnc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.40
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
ICAM1 P05362 1/20 0.32
SELE P16581 1/20 0.32
TRPM8 Q7Z2W7 1/20 0.31
CLK1 P49759 1/20 0.31
DYRK1A Q13627 1/20 0.31
DYRK1B Q9Y463 1/20 0.31
GPR119 Q8TDV5 2/20 0.30
PIK3CA P42336 1/20 0.30
MTOR P42345 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2475954 0.82 ALDH1A1 (0.38) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL2507311 0.80 HCAR2 (0.46) MLYCDALDH1A1KDM4EMEN1KMT2A
SCHEMBL309169 0.77 ALDH1A1 (0.50) ALDH1A1KDM4EATM
SCHEMBL4818530 0.75 HPGD (0.43) MLYCDALDH1A1KDM4EMEN1KMT2A
SCHEMBL1642738 0.74 MLYCD (0.51) MLYCDALDH1A1KDM4EMEN1KMT2A
SCHEMBL1450741 0.74
SCHEMBL2884934 0.72 ALDH1A1 (0.35) ALDH1A1KDM4EMEN1KMT2AATM
SCHEMBL434252 0.72 ALDH1A1 (0.59) MLYCDALDH1A1KDM4EMEN1KMT2A
SCHEMBL4056048 0.72 ATM (0.59) MLYCDALDH1A1KDM4EMEN1KMT2A
SCHEMBL308467 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7365174-B2 Azalide and azalactam derivatives and method for producing the same MEIJI SEIKA KAISHA, LTD. (JP) 2008-04-29 US disclosed
US-20070042974-A1 Nozel azalide and azalactam derivatives and method for producing the same MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070042974-A1 Nozel azalide and azalactam derivatives and method for producing the same BCL6, NR4A1, NR4A2 MLYCD 3984/4885ALDH1A1 1363/4885KDM4E 1300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.