SCHEMBL482268

SCHEMBL482268

CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)OS(=O)(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
VNN1 O95497 13/20 0.59
PTGS1 P23219 1/20 0.46
KCNH2 Q12809 1/20 0.46
HTT P42858 1/20 0.35
ATM Q13315 1/20 0.35
PRSS1 P07477 1/20 0.35
CTSG P08311 1/20 0.35
CTRB1 P17538 1/20 0.35
CMA1 P23946 1/20 0.35
CA12 O43570 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pantothenic Acid, Racemic SCHEMBL482267 0.81 VNN1 (0.61) VNN1PTGS1KCNH2
Pantothenic Acid SCHEMBL482266 0.81 VNN1 (0.61) VNN1PTGS1KCNH2
SCHEMBL3754662 0.80 PTGS1 (0.55) VNN1PTGS1KCNH2CA12CA14
SCHEMBL8039883 0.79 PTGS1 (0.54) VNN1PTGS1KCNH2
SCHEMBL29250117 0.79 PTGS1 (0.54) VNN1PTGS1KCNH2
SCHEMBL8417455 0.79 VNN1 (0.68) VNN1PTGS1KCNH2
SCHEMBL8417457 0.79 VNN1 (0.68) VNN1PTGS1KCNH2
SCHEMBL28332287 0.78 PTGS1 (0.52) VNN1PTGS1KCNH2
Alcohol SCHEMBL27660651 0.77 VNN1 (0.65) VNN1PTGS1KCNH2
SCHEMBL28416351 0.77 PTGS1 (0.51) VNN1PTGS1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2411352-A2 ANTIVIRAL COMPOUNDS AND USES THEREOF Abbott Laboratories (US) 2012-02-01 EP disclosed
WO-2010111436-A2 ANTIVIRAL COMPOUNDS AND USES THEREOF ABBOTT LABORATORIES (US) 2010-09-30 WO disclosed