SCHEMBL4824917

SCHEMBL4824917

CCOP(=O)(CC)OC(c1ccccc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.51
MAPT P10636 2/20 0.49
MAPK1 P28482 2/20 0.49
TSHR P16473 2/20 0.47
ALDH1A1 P00352 2/20 0.44
LMNA P02545 1/20 0.44
ACHE P22303 1/20 0.44
NPSR1 Q6W5P4 2/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KCNH2 Q12809 1/20 0.42
KDM4E B2RXH2 1/20 0.41
AOX1 Q06278 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247699 0.85 POLB (0.50) POLBMAPTMAPK1TSHRALDH1A1
SCHEMBL8923129 0.83 GAA (0.50) POLBTSHRLMNANPSR1GAA
SCHEMBL2213672 0.82 POLB (0.54) POLBMAPTMAPK1TSHRALDH1A1
SCHEMBL8723616 0.82 TSHR (0.42) MAPTTSHRALOX15GAAMEN1
SCHEMBL8718625 0.81 L3MBTL1 (0.42) TSHRL3MBTL1
SCHEMBL10710716 0.75 MAPT (0.59) POLBMAPTMAPK1TSHRALDH1A1
SCHEMBL7386425 0.74 POLB (0.53) POLBMAPTMAPK1TSHRALDH1A1
SCHEMBL27654581 0.74 MAPT (0.57) POLBMAPTMAPK1TSHRALDH1A1
SCHEMBL4227917 0.73 ACP3 (0.53) POLBTSHRALDH1A1NPSR1L3MBTL1
SCHEMBL11126523 0.73 POLB (0.43) POLBMAPTMAPK1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7445877-B2 Charge transport materials having a central disulfane linkage SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-11-04 US disclosed
US-7326506-B2 Bridged charge transport materials having a central sulfur atom linkage SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-02-05 US disclosed
EP-1600821-B1 Bridged charge transport materials having a central sulfur atom linkage SAMSUNG ELECTRONICS CO LTD (KR) 2007-02-28 EP disclosed
US-7083863-B2 Luminous element and method for preparation thereof MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2006-08-01 US disclosed
US-20050277038-A1 Charge transport materials having a central disulfane linkage S-PRINTING SOLUTION CO., LTD. (KR) 2005-12-15 US disclosed
US-20050266329-A1 Bridged charge transport materials having a central sulfur atom linkage S-PRINTING SOLUTION CO., LTD. (KR) 2005-12-01 US disclosed
EP-1600821-A1 Bridged charge transport materials having a central sulfur atom linkage Samsung Electronics Co., Ltd. (KR) 2005-11-30 EP disclosed
US-20050194586-A1 Luminous element and method for preparation thereof JOLED INC (JP) 2005-09-08 US disclosed
US-6150065-A 1-(P-AMINOPHENYL)-1,4,4-TRIPHENYLBUTADIENE DERIVATIVE CHARGE TRANSFER COMPOUNDS TAKASAGO INTERNATIONAL CORPORATION (JP) 2000-11-21 US disclosed
US-5080990-A Dinaphthyl (olefin-substituted)arylamines; high photosensitivity; durability KONICA CORPORATION (JP) 1992-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050266329-A1 Bridged charge transport materials having a central sulfur atom linkage NR2E3, NR4A2, NR2C2 POLB 3994/4885MAPT 3071/4885MAPK1 1922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.