Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923129 | 0.83 | GAA (0.50) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL8718625 | 0.82 | L3MBTL1 (0.42) | TSHR | |
| SCHEMBL4824917 | 0.82 | POLB (0.51) | TSHRALOX15GAAKMT2AMEN1 | |
| SCHEMBL4227917 | 0.79 | ACP3 (0.53) | TSHRACP3TDP1KMT2A | |
| SCHEMBL1339347 | 0.78 | TSHR (0.50) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL11808857 | 0.78 | ACP3 (0.49) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL28846668 | 0.78 | CYP1A2 (0.46) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL9616874 | 0.74 | AKR1C3 (0.46) | TSHRTDP1MAPT | |
| SCHEMBL3765408 | 0.74 | TSHR (0.50) | TSHRKMT2AMAPT | |
| SCHEMBL13321998 | 0.73 | ACP3 (0.53) | CA12CA1CA2CA9ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840454-A | Aromatic polycarbonate and electrophotographic photosensitive medium using same | RICOH COMPANY, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |