Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL4825240

CC(C)[SiH](C(C)C)C(C)C.O=C(O)C(F)(F)F

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874292-A Multi-target chimeric peptide compound, preparation method and application thereof 南通大学 2022-08-09 CN claimed
CN-116640100-A Solid-phase synthesis method of fluororalrana 河北圣雪大成制药有限责任公司 2023-08-25 CN disclosed
WO-2023141536-A1 1,3,4,7-TETRAHYDRO-2H-PYRROLO [3',2':5,6] PYRIDO[2,3-B] [1,4] OXAZEPINE BC1-2 INHIBITORS ABBVIE INC. (US) 2023-07-27 WO disclosed
CN-116077720-A Antibacterial double-layer hydrogel dressing and preparation method thereof 西南交通大学 2023-05-09 CN disclosed
CN-109153703-B Immunomodulator 百时美施贵宝公司 2022-09-23 CN disclosed
CN-114874292-A Multi-target chimeric peptide compound, preparation method and application thereof 南通大学 2022-08-09 CN disclosed
CN-107223129-B Immunomodulator 百时美施贵宝公司 2022-01-04 CN disclosed
CN-107207568-B Immunomodulator 百时美施贵宝公司 2021-12-10 CN disclosed
EP-3423470-B1 IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2021-08-18 EP disclosed
US-20210213010-A1 TLR7/8 AGONISTS AND LIPOSOME COMPOSITIONS DANMARKS TEKNISKE UNIVERSITET (DK) 2021-07-15 US disclosed
US-20140294898-A1 MACROCYCLIC INHIBITORS OF THE PD-1/PD-L1 AND CD80(B7-1)/PD-L1 PROTEIN/PROTEIN INTERACTIONS BRISTOL-MYERS SQUIBB COMPANY 2014-10-02 US disclosed
WO-2014151634-A1 MACROCYCLIC INHIBITORS OF THE PD-1/PD-L1 AND CD80(B7-1)/PD-L1 PROTEIN/PROTEIN INTERACTIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2014-09-25 WO disclosed
US-7425608-B2 Method of making metallopeptides PALATIN TECHNOLOGIES, INC. (US) 2008-09-16 US disclosed
US-20060240481-A1 Melanocortin Metallopeptode Combinatorial Libraries and Applications PALATIN TECHNOLOGIES, INC. (US) 2006-10-26 US disclosed
US-7049398-B1 Melanocortin metallopeptide constructs, combinatorial libraries and applications PALATIN TECHNOLOGIES, INC. (US) 2006-05-23 US disclosed
US-20060003386-A1 Combinatorial library of different sequence peptide members synthesized on solid phase, where each constituent library member includes peptide sequence of three or more amino acid residues bound to solid phase characterized by sequence of two or more amino acid residues forming a metal ion-binding domain PALATIN TECHNOLOGIES, INC. (US) 2006-01-05 US disclosed
US-6660832-B1 Cyclic peptide compounds with fused benzene rings; solid phase synthesis thereof; use as antibiotic to treat bacterial infection in mammals; may work by binding to RNA targets ISIS PHARMACEUTICALS, INC. 2003-12-09 US disclosed
US-20020012948-A1 Metallopeptide combinatorial libraries and applications PALATIN TECHNOLOGIES, INC. 2002-01-31 US disclosed
EP-1027370-A2 A METHOD FOR MAPPING THE ACTIVE SITES BOUND BY ENZYMES THAT COVALENTLY MODIFY SUBSTRATE MOLECULES PEPTIDE THERAPEUTICS LIMITED (GB) 2000-08-16 EP disclosed
WO-1999023109-A2 A METHOD FOR MAPPING THE ACTIVE SITES BOUND BY ENZYMES THAT COVALENTLY MODIFY SUBSTRATE MOLECULES PEPTIDE THERAPEUTICS LIMITED (GB) 1999-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020012948-A1 Metallopeptide combinatorial libraries and applications SPPL2B, METAP2, PTMS ALDH1A1 4694/4885TP53 1789/4885TSHR 1178/4885
US-20140294898-A1 MACROCYCLIC INHIBITORS OF THE PD-1/PD-L1 AND CD80(B7-1)/PD-L1 PROTEIN/PROTEIN INTERACTIONS CD274, PDCD1, PDCD1LG2 ALDH1A1 3138/4885TP53 100/4885TSHR 1405/4885
US-20210213010-A1 TLR7/8 AGONISTS AND LIPOSOME COMPOSITIONS TLR7, TLR9, TLR8 ALDH1A1 4407/4885TP53 2289/4885TSHR 688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.