⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL16289159 | 0.92 | — | — | |
| Trifluoroacetic Acid SCHEMBL4825240 | 0.91 | ALDH1A1 (0.32) | — | |
| Trifluoroacetic Acid SCHEMBL16288044 | 0.88 | — | — | |
| Trifluoroacetic Acid SCHEMBL995275 | 0.88 | TP53 (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL21046091 | 0.84 | ATR (0.32) | — | |
| Trifluoroacetic Acid SCHEMBL1890860 | 0.84 | TP53 (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL21046071 | 0.83 | DPP8 (0.31) | — | |
| Trifluoroacetic Acid SCHEMBL16394297 | 0.82 | — | — | |
| Trifluoroacetic Acid SCHEMBL7065544 | 0.82 | — | — | |
| Trifluoroacetic Acid SCHEMBL4827865 | 0.80 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228509-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | ABBVIE INC (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240166689-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-23 | — | — | US | disclosed |
| US-11964990-B2 | 1,3,4,7-tetrahydro-2H-pyrrolo[3′,2′:5,6]pyrido[2,3-b][1,4]oxazepine bcl-2 inhibitors | ABBVIE INC. (US) | 2024-04-23 | — | — | US | disclosed |
| WO-2024069229-A2 | BIOLOGICALLY ACTIVE COMPOUNDS | SUTURA THERAPEUTICS LTD (GB) | 2024-04-04 | — | — | WO | disclosed |
| US-20240058450-A1 | BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same | ABBVIE INC (US) | 2024-02-22 | — | — | US | disclosed |
| US-11897864-B2 | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE INC. (US) | 2024-02-13 | — | — | US | disclosed |
| US-20240043404-A1 | APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBVIE INC. (US) | 2024-02-08 | — | — | US | disclosed |
| US-11891457-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-02-06 | — | — | US | disclosed |
| US-20230399340-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | ABBVIE INC (US) | 2023-12-14 | — | — | US | disclosed |
| US-11786519-B2 | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20060189636-A1 | Inhibitors of E1 activating enzymes | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-08-24 | — | — | US | disclosed |
| US-20050037974-A1 | Affinity markers for human serum albumin | CONJUCHEM, INC. (CA) | 2005-02-17 | — | — | US | disclosed |
| EP-1485354-A1 | SULFONYLAMINO-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003076401-A1 | SULFONYLAMINO-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-09-18 | — | — | WO | disclosed |
| US-20030032035-A1 | Microfluidic device for analyzing nucleic acids and/or proteins, methods of preparation and uses thereof | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2003-02-13 | — | — | US | disclosed |
| WO-2002089972-A1 | MICROFLUIDIC DEVICE FOR ANALYZING NUCLEIC ACIDS AND/OR PROTEINS, METHODS OF PREPARATION AND USES THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2002-11-14 | — | — | WO | disclosed |
| EP-1056474-B1 | AFFINITY MARKERS FOR HUMAN SERUM ALBUMIN | CONJUCHEM INC (CA) | 2002-06-12 | — | — | EP | disclosed |
| EP-1199566-A1 | Methods of screening affinity marker libraries | Conjuchem, Inc. (CA) | 2002-04-24 | — | — | EP | disclosed |
| EP-1056474-A2 | AFFINITY MARKERS FOR HUMAN SERUM ALBUMIN | ConjuChem, Inc. (CA) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999024075-A2 | AFFINITY MARKERS FOR HUMAN SERUM ALBUMIN | CONJUCHEM, INC. (CA) | 1999-05-20 | — | — | WO | disclosed |