Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4826633 | 0.92 | TOP2A (0.45) | KDM4EMAPTTOP2ACYP3A4CYP1A2 | |
| SCHEMBL4826837 | 0.89 | ALDH1A1 (0.48) | KDM4EMAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL21533507 | 0.84 | TOP2A (0.47) | KDM4EMAPTTOP2ACYP3A4CYP1A2 | |
| SCHEMBL4826976 | 0.84 | ALDH1A1 (0.55) | KDM4EMAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL4823915 | 0.83 | TOP2A (0.51) | KDM4EMAPTTOP2ACYP3A4CYP1A2 | |
| SCHEMBL6260953 | 0.83 | ALDH1A1 (0.46) | MAPTCYP3A4ALDH1A1SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL4824474 | 0.83 | ALDH1A1 (0.54) | KDM4EMAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL23673315 | 0.80 | MAPT (0.51) | KDM4EMAPTTOP2ACYP3A4CYP1A2 | |
| SCHEMBL4826980 | 0.80 | SMN1; SMN2 (0.55) | KDM4EMAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL14570539 | 0.80 | TOP2A (0.53) | KDM4EMAPTTOP2ACYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | claimed |
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | claimed |
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | disclosed |
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | disclosed |
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | disclosed |
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | KRT18, CDC73, JUP | KDM4E 599/4885MAPT 1947/4885TOP2A 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.