SCHEMBL4825409

SCHEMBL4825409

CCCS(=O)(=O)O/N=C(/C#N)c1ccc(OC)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 2/20 0.39
NQO2 P16083 1/20 0.38
MAPT P10636 3/20 0.37
NR1I2 O75469 1/20 0.37
NPSR1 Q6W5P4 2/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
NFKB1 P19838 1/20 0.37
APEX1 P27695 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37
TDP1 Q9NUW8 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4825418 1.00 RECQL (0.39) RECQLNQO2MAPTNR1I2NPSR1
SCHEMBL7558887 0.92 PTGS2 (0.40) RECQLNQO2MAPTNR1I2NPSR1
SCHEMBL7558881 0.92 PTGS2 (0.40) RECQLNQO2MAPTNR1I2NPSR1
SCHEMBL297395 0.91 NQO2 (0.40) NQO2MAPTNR1I2NPSR1ALDH1A1
SCHEMBL36535 0.91 NQO2 (0.40) NQO2MAPTNR1I2NPSR1ALDH1A1
SCHEMBL1755727 0.90 PTGS2 (0.38) PTGS2
SCHEMBL4354862 0.90 PTGS2 (0.38) PTGS2
SCHEMBL1357769 0.90 PTGS2 (0.38) PTGS2
SCHEMBL4354857 0.90 PTGS2 (0.38) PTGS2
SCHEMBL18819681 0.88 PARP10 (0.40) MAPTNPSR1ALDH1A1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7399575-B2 Laminated photosensitive relief printing original plate and method for producing the relief printing plate TOKYO OHKA KOGYO CO., LTD. (JP) 2008-07-15 US disclosed
US-20080166657-A1 Resist composition for bulkhead formation, bulkhead of EL display device and EL display device SUGIMOTO YASUAKI 2008-07-10 US disclosed
US-7323284-B2 Negative type radiation sensitive resin composition JSR CORPORATION (JP) 2008-01-29 US disclosed
US-20060177771-A1 Laminated photosensitive relief printing original plate and method for producing the relief printing plate KODAK AMERICAS LTD. 2006-08-10 US disclosed
US-20050236967-A1 Resist composition for separator formation, separator of EL display device and EL display device TOKYO OHKA KOGYO CO., LTD. (JP) 2005-10-27 US disclosed
WO-2005026836-A2 LAMINATED PHOTOSENSITIVE RELIEF PRINTING ORIGINAL PLATE AND METHOD FOR PRODUCING THE RELIEF PRINTING PLATE TOKYO OHKA KOGYO CO., LTD. (JP) 2005-03-24 WO disclosed
US-6835530-B2 Base material for lithography TOKYO OHKA KOGYO CO., LTD. (JP) 2004-12-28 US disclosed
US-20040121260-A1 Base material for lithography TOKYO OHKA KOGYO CO., LTD. 2004-06-24 US disclosed
US-20030022095-A1 Negative type radiation sensitive resin composition JSR CORPORATION (JP) 2003-01-30 US disclosed
US-6268108-B1 MIXTURE OF COMPOUND FORMING ACID UPON EXPOSURE OF ACTINIC RADIATION, COMPOUND CAPABLE OF CROSSLINKING, DYE AND SOLVENT TOKYO OHKA KOGYO CO., LTD. (JP) 2001-07-31 US disclosed