Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 4/20 | 0.47 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.46 |
| ▸ | PLK1 | P53350 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4825688 | 1.00 | ACLY (0.47) | ACLYIGF2BP2CTDSP1PLK1HDAC2 | |
| SCHEMBL4826497 | 0.95 | CTDSP1 (0.50) | CTDSP1PLK1KCNK2KCNK10NPC1 | |
| SCHEMBL4826504 | 0.95 | CTDSP1 (0.50) | CTDSP1PLK1KCNK2KCNK10NPC1 | |
| SCHEMBL4830819 | 0.94 | ACLY (0.53) | ACLYIGF2BP2CTDSP1PLK1HDAC2 | |
| SCHEMBL4830825 | 0.94 | ACLY (0.53) | ACLYIGF2BP2CTDSP1PLK1HDAC2 | |
| SCHEMBL4831288 | 0.92 | IGF2BP2 (0.55) | ACLYIGF2BP2CTDSP1PLK1HDAC2 | |
| SCHEMBL4831282 | 0.92 | IGF2BP2 (0.55) | ACLYIGF2BP2CTDSP1PLK1HDAC2 | |
| SCHEMBL4833874 | 0.92 | PLK1 (0.47) | IGF2BP2PLK1HDAC2KCNK2KCNK10 | |
| SCHEMBL4833858 | 0.92 | PLK1 (0.47) | IGF2BP2PLK1HDAC2KCNK2KCNK10 | |
| SCHEMBL4827028 | 0.91 | CTDSP1 (0.46) | IGF2BP2CTDSP1PLK1KCNK2KCNK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7420083-B2 | Substituted aryloximes | WYETH (US) | 2008-09-02 | — | — | US | claimed |
| US-20050070584-A1 | Substituted aryloximes | WYETH (US) | 2005-03-31 | — | — | US | claimed |
| US-20080293790-A1 | SUBSTITUTED ARYL OXIMES | WYETH (US) | 2008-11-27 | — | — | US | disclosed |
| US-7420083-B2 | Substituted aryloximes | WYETH (US) | 2008-09-02 | — | — | US | disclosed |
| US-20050070584-A1 | Substituted aryloximes | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070584-A1 | Substituted aryloximes | AHR, NQO1, AOX1 | ACLY 1961/4885IGF2BP2 3245/4885CTDSP1 2943/4885 |
| US-20080293790-A1 | SUBSTITUTED ARYL OXIMES | HCCS, AOX1, TET2 | ACLY 1508/4885IGF2BP2 3268/4885CTDSP1 2524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.