Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | CPA3 | P15088 | 3/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098207 | 0.81 | MMP8 (0.46) | CYP1A2MMEMMP8 | |
| SCHEMBL392827 | 0.81 | CYP1A2 (0.70) | CYP1A2MDM2ALPIPKMPTGS1 | |
| SCHEMBL16218015 | 0.81 | CYP1A2 (0.53) | CYP1A2MDM2ALPIPKMPTGS1 | |
| SCHEMBL28377626 | 0.79 | CYP1A2 (0.67) | CYP1A2MDM2ALPIPKMPTGS1 | |
| SCHEMBL27876635 | 0.79 | CYP1A2 (0.67) | CYP1A2MDM2ALPIPKMPTGS1 | |
| SCHEMBL28314499 | 0.79 | CYP1A2 (0.67) | CYP1A2MDM2ALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL7304155 | 0.79 | CYP1A2 (0.67) | CYP1A2MDM2ALPIPKMPTGS1 | |
| SCHEMBL7349956 | 0.78 | CYP1A2 (0.59) | CYP1A2MDM2ALPIPKMPTGS1 | |
| SCHEMBL4310520 | 0.74 | CYP1A2 (0.55) | CYP1A2MDM2ALPIPKMPTGS1 | |
| SCHEMBL6896938 | 0.74 | ALPI (0.57) | CYP1A2MDM2ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324975-A2 | DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS | Bristol-Myers Squibb Company (US) | 2003-07-09 | — | — | EP | claimed |
| US-20020111512-A1 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY | 2002-08-15 | — | — | US | claimed |
| WO-2002028809-A2 | DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-04-11 | — | — | WO | claimed |
| US-7388098-B2 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | disclosed |
| EP-1324975-B1 | DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS | BRISTOL MYERS SQUIBB CO (US) | 2005-11-16 | — | — | EP | disclosed |
| EP-1140818-B1 | AMIDOMALONAMIDES AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEINASE | AVENTIS PHARMA INC (US) | 2003-09-10 | — | — | EP | disclosed |
| EP-1324975-A2 | DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS | Bristol-Myers Squibb Company (US) | 2003-07-09 | — | — | EP | disclosed |
| US-20020111512-A1 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY | 2002-08-15 | — | — | US | disclosed |
| WO-2002028809-A2 | DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-04-11 | — | — | WO | disclosed |
| US-6329550-B1 | FOR THERAPY OF EMPHYSEMA, OSTEOPOROSIS, RHEUMATOID ARTHRITIS AND NEOPLASTIC DISEASES | AVENTIS PHARMACEUTICALS INC. | 2001-12-11 | — | — | US | disclosed |
| EP-1140818-A1 | AMIDOMALONAMIDES AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEINASE | Aventis Pharmaceuticals Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040552-A1 | AMIDOMALONAMIDES AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEINASE | AVENTIS PHARMACEUTICALS INC. (US) | 2000-07-13 | — | — | WO | disclosed |
| CN-1110865-A | Amino acid derivatives | EISAI CO LTD (JP) | 1995-10-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111512-A1 | Dynamic resolution of isomers and resolved isomers | DHCR24, LPAR1, SLC7A1 | CYP1A2 1752/4885MDM2 1560/4885ALPI 1764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.