Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | CPA3 | P15088 | 3/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24405183 | 0.83 | CTSB (0.48) | CYP1A2MDM2MMP8 | |
| SCHEMBL392827 | 0.81 | CYP1A2 (0.70) | CYP1A2MDM2ALPIPKMPTGS1 | |
| SCHEMBL28141249 | 0.81 | CYP1A2 (0.48) | CYP1A2MDM2ALPIPKMPTGS1 | |
| SCHEMBL4826237 | 0.81 | CYP1A2 (0.53) | CYP1A2MDM2ALPIPKMPTGS1 | |
| SCHEMBL27418403 | 0.79 | CYP1A2 (0.47) | CYP1A2MDM2ALPIPKMPTGS1 | |
| SCHEMBL2600708 | 0.79 | HPGD (0.51) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL13367286 | 0.79 | SLC7A5 (0.63) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL11499279 | 0.79 | SLC7A5 (0.63) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL18383090 | 0.79 | HPGD (0.51) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL28377626 | 0.79 | CYP1A2 (0.67) | CYP1A2MDM2ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108089380-A | A kind of single side bipolar electrode and a kind of method of electric responsive material surface configuration | 华南师范大学 | 2018-05-29 | — | — | CN | disclosed |
| US-9498420-B2 | Cosmetic compositions and methods for inhibiting melanin synthesis | THE PROCTER & GAMBLE COMPANY (US) | 2016-11-22 | — | — | US | disclosed |
| US-20140328775-A1 | Cosmetic Compositions and Methods For Inhibiting Melanin Synthesis | THE PROCTER & GAMBLE COMPANY (US) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140328775-A1 | Cosmetic Compositions and Methods For Inhibiting Melanin Synthesis | TYR, MITF, DBH | CYP1A2 1725/4885MDM2 4350/4885ALPI 1631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.