SCHEMBL4826258

SCHEMBL4826258

CCCCCc1cccc(C(=O)O)c1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 3/20 0.52
MCL1 Q07820 3/20 0.52
PPARA Q07869 3/20 0.52
BCL2L1 Q07817 2/20 0.52
BAK1 Q16611 2/20 0.52
KAT8 Q9H7Z6 2/20 0.52
PPARG P37231 2/20 0.52
SAE1 Q9UBE0 2/20 0.52
EP300 Q09472 1/20 0.52
KAT2A Q92830 1/20 0.52
KAT2B Q92831 1/20 0.52
KAT5 Q92993 1/20 0.52
CYSLTR2 Q9NS75 7/20 0.47
CYSLTR1 Q9Y271 7/20 0.47
MMP2 P08253 2/20 0.46
F7 P08709 2/20 0.46
F3 P13726 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15228015 0.89 PTPN11 (0.48) BIDMCL1PPARABCL2L1BAK1
Bicarbonate SCHEMBL17473105 0.85 BID (0.49) BIDMCL1PPARABCL2L1BAK1
SCHEMBL623528 0.84 FOLH1 (0.59) BIDMCL1PPARABCL2L1BAK1
SCHEMBL5171335 0.84 FOLH1 (0.59) BIDMCL1PPARABCL2L1BAK1
SCHEMBL29902881 0.84 FOLH1 (0.59) BIDMCL1PPARABCL2L1BAK1
SCHEMBL29254314 0.84 CLCN2 (0.54) KDM4EMAPTALOX15
SCHEMBL27547212 0.84 LMNA (0.44) BIDMCL1PPARABCL2L1BAK1
Bicarbonate SCHEMBL17473075 0.84 BID (0.51) BIDMCL1PPARABCL2L1BAK1
SCHEMBL28360757 0.83 GABRP (0.43) BIDMCL1PPARABCL2L1BAK1
SCHEMBL11323683 0.82 RARB (0.49) BIDMCL1PPARABCL2L1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7335405-B2 Nematic liquid crystal mixtures for use in bistable display devices NEMOPTIC (FR) 2008-02-26 US disclosed
US-20060249708-A1 Nematic liquid crystal mixtures for use in bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2006-11-09 US disclosed
US-7115307-B2 Nematic liquid crystal mixtures for bistable display device NEMOPTIC (FR) 2006-10-03 US disclosed