Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640908 | 0.81 | TSHR (0.62) | TSHRHSD17B10CYP2A6LOXL2KCNJ1 | |
| SCHEMBL10569888 | 0.81 | TSHR (0.68) | TSHRHSD17B10CYP2A6LOXL2KCNJ1 | |
| SCHEMBL4864848 | 0.81 | TSHR (0.50) | TSHRHSD17B10CYP2A6LOXL2KCNJ1 | |
| SCHEMBL9458406 | 0.81 | TSHR (0.50) | TSHRHSD17B10CYP2A6LOXL2KCNJ1 | |
| SCHEMBL16582463 | 0.79 | TSHR (0.71) | TSHRHSD17B10CYP2A6LOXL2KCNJ1 | |
| SCHEMBL10569117 | 0.79 | TSHR (0.71) | TSHRHSD17B10CYP2A6LOXL2KCNJ1 | |
| SCHEMBL16582531 | 0.79 | TSHR (0.71) | TSHRHSD17B10CYP2A6LOXL2KCNJ1 | |
| SCHEMBL3753968 | 0.78 | HSD17B10 (0.76) | TSHRHSD17B10CYP2A6LOXL2KCNJ1 | |
| SCHEMBL12500343 | 0.77 | LOXL2 (0.62) | TSHRHSD17B10CYP2A6LOXL2KCNJ1 | |
| SCHEMBL10341661 | 0.77 | TSHR (0.58) | TSHRHSD17B10CYP2A6LOXL2KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335405-B2 | Nematic liquid crystal mixtures for use in bistable display devices | NEMOPTIC (FR) | 2008-02-26 | — | — | US | disclosed |
| US-20060249708-A1 | Nematic liquid crystal mixtures for use in bistable display devices | CDC PROPRIETE INTELLECTUELLE (FR) | 2006-11-09 | — | — | US | disclosed |