Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4826294 | 0.81 | C5AR1 (0.40) | C5AR1 | |
| SCHEMBL1328368 | 0.78 | C5AR1 (0.39) | C5AR1 | |
| SCHEMBL4826301 | 0.76 | C5AR1 (0.40) | C5AR1 | |
| SCHEMBL6520800 | 0.76 | ALOX5 (0.43) | C5AR1 | |
| SCHEMBL6523352 | 0.76 | C5AR1 (0.38) | C5AR1 | |
| SCHEMBL6522043 | 0.74 | PPARA (0.49) | — | |
| SCHEMBL1327003 | 0.73 | C5AR1 (0.48) | C5AR1 | |
| SCHEMBL1328376 | 0.73 | C5AR1 (0.40) | C5AR1 | |
| SCHEMBL2138911 | 0.72 | C5AR1 (0.42) | C5AR1 | |
| SCHEMBL1328940 | 0.72 | NPSR1 (0.43) | C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342115-B2 | Binding antagonist and arylpyridine for antiinflammatory agents, cardiovascular disorders and antagonist or agonist and for immunology | NEUROGEN CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |